Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 5/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 3/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10089845 | 0.95 | NTRK1 (0.34) | NTRK1RORCGRM4TGFBR1ABL1 | |
| SCHEMBL10089833 | 0.94 | NTRK1 (0.35) | NTRK1TGFBR1CRHR1HTR3A | |
| SCHEMBL686481 | 0.94 | CRHR1 (0.36) | GRM4CRHR1MALT1 | |
| SCHEMBL13085232 | 0.93 | PDE4B (0.34) | GRM4CRHR1MALT1 | |
| SCHEMBL10089835 | 0.93 | RORC (0.38) | NTRK1RORCGRM4 | |
| SCHEMBL13084989 | 0.90 | CRHR1 (0.35) | GRM4CRHR1MALT1 | |
| SCHEMBL10090039 | 0.90 | CRHR1 (0.35) | NTRK1RORCTGFBR1ABL1CRHR1 | |
| SCHEMBL10089832 | 0.90 | NTRK1 (0.34) | NTRK1RORCGRM4ABL1CRHR1 | |
| SCHEMBL10089478 | 0.90 | DGAT2 (0.35) | NTRK1 | |
| SCHEMBL10075289 | 0.90 | DHODH (0.33) | MALT1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8791143-B2 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2014-07-29 | — | — | US | disclosed |
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010249-A1 | Anthranilic diamide derivatives having cyclic side-chains | DDT, ADCY1, ANTXR2 | NTRK1 4223/4885RORC 3664/4885GRM4 3594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.