SCHEMBL13085239

SCHEMBL13085239

Cc1cc(C#N)cc(C(=O)NC(C)C)c1NC(=O)c1cc(Cn2nnnc2C(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 5/20 0.33
GCK P35557 4/20 0.33
SLC2A1 P11166 4/20 0.32
SLC2A3 P11169 4/20 0.32
SLC2A4 P14672 4/20 0.32
SLC2A2 P11168 1/20 0.32
DHODH Q02127 2/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085533 0.93 SLC2A1 (0.33) KCNH2GCKSLC2A1SLC2A3SLC2A4
SCHEMBL13085530 0.93 EGLN1 (0.32) KCNH2GCKSLC2A1SLC2A3SLC2A4
SCHEMBL13085238 0.92 DHODH (0.32) DHODH
SCHEMBL13085591 0.92 SLC2A1 (0.33) KCNH2GCKSLC2A1SLC2A3SLC2A4
SCHEMBL13090900 0.91 DHODH (0.32) DHODH
SCHEMBL13085531 0.90 RORC (0.35) SLC2A1SLC2A3SLC2A4SLC2A2PDE4B
SCHEMBL10075524 0.90 SLC2A1 (0.36) KCNH2GCKSLC2A1SLC2A3SLC2A4
SCHEMBL13085513 0.90 SLC2A1 (0.34) KCNH2GCKSLC2A1SLC2A3SLC2A4
SCHEMBL10083276 0.89 SLC2A1 (0.34) KCNH2GCKSLC2A1SLC2A3SLC2A4
SCHEMBL13085593 0.88 DHODH (0.32) DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 KCNH2 981/4885GCK 3335/4885SLC2A1 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.