SCHEMBL13085531

SCHEMBL13085531

Cc1cc(C#N)cc(C(=O)NC2CC2)c1NC(=O)c1cc(Cn2nnnc2C(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 3/20 0.35
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPK1 P28482 1/20 0.33
CRHR1 P34998 4/20 0.32
MAPK8 P45983 1/20 0.32
NTRK1 P04629 1/20 0.32
CHRM4 P08173 1/20 0.32
PDE4B Q07343 3/20 0.32
GRM4 Q14833 1/20 0.32
ADORA1 P30542 1/20 0.32
CRHR2 Q13324 2/20 0.32
SLC2A1 P11166 1/20 0.32
SLC2A2 P11168 1/20 0.32
SLC2A3 P11169 1/20 0.32
SLC2A4 P14672 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085521 0.92 CRHR1 (0.36) ALDH1A1L3MBTL1MAPK1CRHR1MAPK8
SCHEMBL13085533 0.92 SLC2A1 (0.33) SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL13085530 0.91 EGLN1 (0.32) SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL13085239 0.90 KCNH2 (0.33) PDE4BSLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL10075532 0.90 CRHR1 (0.36) RORCCRHR1CRHR2SLC2A1SLC2A2
SCHEMBL13085591 0.90 SLC2A1 (0.33) SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL10074911 0.89 CRHR1 (0.34) RORCALDH1A1L3MBTL1MAPK1CRHR1
SCHEMBL13085266 0.88 RORC (0.35) RORCCRHR1MAPK8NTRK1CHRM4
SCHEMBL13085242 0.88 MAPK8 (0.36) CRHR1MAPK8NTRK1PDE4BCRHR2
SCHEMBL11928506 0.88 SLC2A1 (0.34) RORCALDH1A1L3MBTL1MAPK1CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 RORC 3454/4885ALDH1A1 3779/4885L3MBTL1 2405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.