SCHEMBL13085530

SCHEMBL13085530

Cc1cc(C#N)cc(C(=O)NC(C)C2CC2)c1NC(=O)c1cc(Cn2nnnc2C(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.32
IDO1 P14902 1/20 0.32
GCK P35557 1/20 0.32
KCNH2 Q12809 1/20 0.32
SLC2A1 P11166 1/20 0.31
SLC2A2 P11168 1/20 0.31
SLC2A3 P11169 1/20 0.31
SLC2A4 P14672 1/20 0.31
GPR6 P46095 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085520 0.93 IDO1 (0.33) IDO1
SCHEMBL13085239 0.93 KCNH2 (0.33) GCKKCNH2SLC2A1SLC2A2SLC2A3
SCHEMBL11928505 0.91 SLC2A1 (0.34) EGLN1IDO1GCKKCNH2SLC2A1
SCHEMBL13085531 0.91 RORC (0.35) SLC2A1SLC2A2SLC2A3SLC2A4
SCHEMBL13085611 0.90 SLC2A1 (0.33) EGLN1IDO1GCKKCNH2SLC2A1
SCHEMBL13085533 0.90 SLC2A1 (0.33) GCKKCNH2SLC2A1SLC2A2SLC2A3
SCHEMBL13085061 0.90 SLC2A1 (0.32) EGLN1IDO1GCKKCNH2SLC2A1
SCHEMBL13085241 0.89 IDO1 (0.34) IDO1
SCHEMBL11928352 0.89 SLC2A1 (0.33) EGLN1GCKKCNH2SLC2A1SLC2A2
SCHEMBL13085391 0.88 EGLN1 (0.33) EGLN1IDO1GCKKCNH2GPR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 EGLN1 3626/4885IDO1 2000/4885GCK 3335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.