SCHEMBL13085520

SCHEMBL13085520

Cc1cc(Cl)cc(C(=O)NC(C)C2CC2)c1NC(=O)c1cc(Cn2nnnc2C(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.33
MALT1 Q9UDY8 3/20 0.32
DRD4 P21917 1/20 0.31
NAMPT P43490 2/20 0.31
DHODH Q02127 1/20 0.31
MAPK8 P45983 1/20 0.30
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30
CNR1 P21554 2/20 0.30
CNR2 P34972 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13085241 0.95 IDO1 (0.34) IDO1NAMPTMAPK8LMNAPOLB
SCHEMBL13085530 0.93 EGLN1 (0.32) IDO1
SCHEMBL13085238 0.92 DHODH (0.32) MALT1DHODH
SCHEMBL13085521 0.90 CRHR1 (0.36) MALT1MAPK8CNR1CNR2
SCHEMBL13085056 0.89 IDO1 (0.32) IDO1MALT1DRD4
SCHEMBL13085508 0.89 DHODH (0.33) MALT1DHODH
SCHEMBL13084919 0.88 IDO1 (0.33) IDO1MALT1DRD4NAMPTDHODH
SCHEMBL13085542 0.88 DHODH (0.32) DHODH
SCHEMBL13085593 0.87 DHODH (0.32) DHODH
SCHEMBL12113184 0.86 MALT1 (0.36) IDO1MALT1DRD4NAMPTDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-8324390-B2 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2012-12-04 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256195-A1 Tetrazole-substituted anthranilamides as pesticides ANTXR2, PNISR, H1-5 IDO1 2000/4885MALT1 4312/4885DRD4 2648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.