⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18652663 | 0.81 | — | — | |
| SCHEMBL1501122 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL5597403 | 0.81 | ALDH1A1 (0.39) | — | |
| SCHEMBL16328978 | 0.81 | — | — | |
| SCHEMBL16938606 | 0.80 | — | — | |
| SCHEMBL14005132 | 0.80 | TSHR (0.33) | — | |
| SCHEMBL13675273 | 0.79 | — | — | |
| SCHEMBL15576709 | 0.79 | CTSS (0.35) | — | |
| SCHEMBL9152252 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL27093631 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220102-B1 | BASELESS NUCLEOTIDE ANALOGUES AND USES THEREOF | CLINICAL MICRO SENSORS INC (US) | 2014-04-16 | — | — | EP | disclosed |
| US-7820391-B2 | having relatively high coupling efficiency that are particularly useful in nucleic acid synthesis; has a redox active moiety comprising a ferrocene derivative; non-nucleotide ferrocene labels; kits | OSMETECH MOLECULAR DIAGNOSTICS (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820391-B2 | having relatively high coupling efficiency that are particularly useful in nucleic acid synthesis; has a redox active moiety comprising a ferrocene derivative; non-nucleotide ferrocene labels; kits | OSMETECH MOLECULAR DIAGNOSTICS (US) | 2010-10-26 | — | — | US | disclosed |
| US-20090155795-A1 | BASELESS NUCLEOTIDE ANALOGUES AND USES THEREOF | OSMETECH MOLECULAR DIAGNOSTICS (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155795-A1 | BASELESS NUCLEOTIDE ANALOGUES AND USES THEREOF | OSMETECH MOLECULAR DIAGNOSTICS (US) | 2009-06-18 | — | — | US | disclosed |
| WO-2009061941-A2 | BASELESS NUCLEOTIDE ANALOGUES AND USES THEREOF | OSMETECH MOLECULAR DIAGNOSTICS (US) | 2009-05-14 | — | — | WO | disclosed |