Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13086369 | 0.80 | EPHX2 (0.40) | POLBCASP6TSHRALDH1A1KDM4E | |
| SCHEMBL13416246 | 0.80 | HDAC6 (0.51) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL13086303 | 0.79 | PTGS2 (0.39) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL13086591 | 0.79 | PTGS2 (0.41) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL13086364 | 0.76 | HPGD (0.40) | POLBCASP6TSHRALDH1A1KDM4E | |
| SCHEMBL13086523 | 0.74 | ALDH1A1 (0.41) | POLBCASP6TSHRALDH1A1KDM4E | |
| SCHEMBL13086256 | 0.73 | ALDH1A1 (0.42) | POLBCASP6TSHRALDH1A1KDM4E | |
| SCHEMBL5492174 | 0.71 | TSHR (0.76) | TSHR | |
| SCHEMBL8122418 | 0.69 | TSHR (0.78) | TSHR | |
| SCHEMBL9019404 | 0.69 | TSHR (0.66) | TSHRALDH1A1KDM4EGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118968-A1 | NO-DONOR ASPIRIN DERIVATIVES | NICOX S.A. (FR) | 2010-10-21 | — | — | WO | disclosed |