Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL5878128 | 0.87 | CHRM2 (0.41) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT | |
| Toluene SCHEMBL28537188 | 0.85 | NPC1 (0.41) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT | |
| SCHEMBL323220 | 0.83 | CHRM2 (0.44) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT | |
| SCHEMBL322281 | 0.83 | CHRM2 (0.44) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT | |
| SCHEMBL323060 | 0.83 | CHRM2 (0.44) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT | |
| Water SCHEMBL4817063 | 0.82 | CHRM2 (0.42) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT | |
| SCHEMBL10306685 | 0.82 | CHRM2 (0.42) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT | |
| Isobutane SCHEMBL11057630 | 0.80 | CHRM2 (0.43) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT | |
| Toluene SCHEMBL7621320 | 0.80 | HPGD (0.51) | ALDH1A1SMN1; SMN2KDM4EGAARAB9A | |
| SCHEMBL1426691 | 0.79 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1THRBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11845758-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | PRINTNET KERESKEDELMI ÉS SZOLGÁLTATÓ KFT. (HU) | 2023-12-19 | — | — | US | disclosed |
| EP-4276102-A2 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | Printnet Kereskedelmi és Szolgáltató Kft. (HU) | 2023-11-15 | — | — | EP | disclosed |
| US-20230339959-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | EÖTVÖS LORÁND TUDOMÁNYEGYETEM (HU) | 2023-10-26 | — | — | US | disclosed |
| US-11746112-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | EÖTVÖS LORÁND TUDOMÁNYEGYETEM (HU) | 2023-09-05 | — | — | US | disclosed |
| EP-3781263-B1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | PRINTNET KERESKEDELMI ES SZOLGALTATO KFT (HU) | 2023-07-12 | — | — | EP | disclosed |
| US-20210087201-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | EÖTVÖS LORÁND TUDOMÁNYEGYETEM (HU) | 2021-03-25 | — | — | US | disclosed |
| EP-3781263-A2 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | Printnet Kereskedelmi és Szolgátató Kft. (HU) | 2021-02-24 | — | — | EP | disclosed |
| US-8273890-B2 | Thiophene-imidazopyridines | 4SC AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-8053473-B2 | Antibacterial agent comprising 7, 10-dihydroxy-8(E)-octadecenoic acid | KYUNG POOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2011-11-08 | — | — | US | disclosed |
| US-20100278833-A1 | THIOPHENE-IMIDAZOPYRIDINES | 4SC AG (DE) | 2010-11-04 | — | — | US | disclosed |
| US-4394515-A | 10,11-Dihydro-11-oxodibenzo[b,f]thiepin compounds | MERCK & CO., INC. (US) | 1983-07-19 | — | — | US | disclosed |
| US-4372971-A | Heterocyclic prostaglandin type compounds, medicaments containing them and processes for the preparation and use of these heterocyclic compounds and medicaments | GRUENENTHAL GMBH (DE) | 1983-02-08 | — | — | US | disclosed |
| EP-0069810-A1 | Novel dibenzoxepins, their preparation, compositions containing them and the use of dibenzoxepins in the treatment of allergic conditions | MERCK & CO. INC. (US) | 1983-01-19 | — | — | EP | disclosed |
| EP-0000978-B1 | 7-AND 8-SUBSTITUTED -10,11-DIHYDRO-11-OXODIBENZO (B,F) THIEPIN DERIVATIVES, THEIR PRODUCTION AND THEIR PARMACEUTICAL COMPOSITIONS | MERCK & CO. INC. (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4322422-A | Oxalylated amidinohydrazones, method for preparing same and use as insect and fire ant control agents | AMERICAN CYANAMID CO. (US) | 1982-03-30 | — | — | US | disclosed |
| US-4282365-A | Dibenz[b,e]oxepin compounds | MERCK & CO., INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4278763-A | Diagnostic agents for the detection of proteolytic enzymes | BOEHRINGER MANNHEIM GMBH (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4263207-A | ANTIALLERGENS | MERCK & CO., INC. (US) | 1981-04-21 | — | — | US | disclosed |
| EP-0011067-A1 | Prostaglandin antagonists, their production and their pharmaceutical compositions | MERCK & CO. INC. (US) | 1980-05-28 | — | — | EP | disclosed |
| EP-0000978-A1 | 7-and 8-substituted -10,11-dihydro-11-oxodibenzo (b,f) thiepin derivatives, their production and their parmaceutical compositions | MERCK & CO. INC. (US) | 1979-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11845758-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | MYH2, MYLK2, MYO1B | ALDH1A1 2854/4885L3MBTL1 4080/4885THRB 1682/4885 |
| US-20100278833-A1 | THIOPHENE-IMIDAZOPYRIDINES | PIKFYVE, PIP4K2B, PIP5K1B | ALDH1A1 3695/4885L3MBTL1 3200/4885THRB 2553/4885 |
| US-20210087201-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | MYH2, MYLK2, MYO1B | ALDH1A1 2854/4885L3MBTL1 4080/4885THRB 1682/4885 |
| US-11746112-B2 | Pharmaceutically effective compounds inhibiting selectively the myosin 2 isoforms | MYH2, MYLK2, MYO1B | ALDH1A1 2854/4885L3MBTL1 4080/4885THRB 1682/4885 |
| US-20230339959-A1 | PHARMACEUTICALLY EFFECTIVE COMPOUNDS INHIBITING SELECTIVELY THE MYOSIN 2 ISOFORMS | MYH2, MYLK2, MYO1B | ALDH1A1 2854/4885L3MBTL1 4080/4885THRB 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.