Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.32 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322281 | 1.00 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM3CYP1A2 | |
| SCHEMBL323220 | 1.00 | CHRM2 (0.44) | CHRM2CHRM4CHRM5CHRM3CYP1A2 | |
| Water SCHEMBL4817063 | 0.98 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM3CYP1A2 | |
| SCHEMBL10306685 | 0.98 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM3CYP1A2 | |
| Benzene SCHEMBL5878128 | 0.96 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM3CYP1A2 | |
| Isobutane SCHEMBL11057630 | 0.92 | CHRM2 (0.43) | CHRM2CHRM4CHRM5CHRM3CYP1A2 | |
| Hexane SCHEMBL11488442 | 0.89 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM3CYP1A2 | |
| SCHEMBL8207932 | 0.84 | CHRM2 (0.39) | CHRM2CHRM4CHRM5CHRM3FEN1 | |
| Toluene SCHEMBL1308697 | 0.83 | ALDH1A1 (0.43) | CHRM2CHRM4CHRM5CHRM3FEN1 | |
| Benzene SCHEMBL11465351 | 0.82 | CHRM2 (0.36) | CHRM2CHRM4CHRM5CHRM3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140357711-A1 | Amooranin Compounds and Analogs Thereof and Related Methods of Use | ENZYME BIO SYSTEMS (US) | 2014-12-04 | — | — | US | claimed |
| WO-2013101719-A2 | AMOORANIN COMPOUNDS AND ANALOGS THEREOF AND RELATED METHODS OF USE | NORTHEAST OHIO MEDICAL UNIVERSITY (US) | 2013-07-04 | — | — | WO | claimed |
| US-4801358-A | DIMETHYLACETAMIDE | BERG LLOYD (US) | 1989-01-31 | — | — | US | claimed |
| US-4801357-A | DIMETHYL SULFOXIDE | BERG LLOYD (US) | 1989-01-31 | — | — | US | claimed |
| US-4440690-A | Process for the synthesis of 6-bromo-17,21-dihydroxy 3,11,20-trioxo-1,4-pregnadienes 17,21-diesters | SCHERING CORPORATION (US) | 1984-04-03 | — | — | US | claimed |
| JP-60142991-A | — | — | None | — | — | JP | disclosed |
| US-12617777-B2 | GPR84 antagonists and uses thereof | Liminal Biosciences Limited (GB) | 2026-05-05 | — | — | US | disclosed |
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |
| US-20250223292-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | VERTEX PHARMACEUTICALS INCORPORATED | 2025-07-10 | — | — | US | disclosed |
| EP-4534538-A2 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | Vertex Pharmaceuticals Incorporated (US) | 2025-04-09 | — | — | EP | disclosed |
| WO-2025067111-A1 | MENIN-MLL INTERACTION INHIBITOR AND PREPARATION METHOD THEREFOR, AND APPLICATION | 苏州必扬医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |
| EP-4190786-B1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | VERTEX PHARMA (US) | 2025-02-26 | — | — | EP | disclosed |
| US-4401595-A | 4-Allyl azetidinone intermediate for β-lactam antibacterial agents | BEECHAM GROUP LIMITED (GB) | 1983-08-30 | — | — | US | disclosed |
| EP-0083975-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |
| US-4388467-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1983-06-14 | — | — | US | disclosed |
| US-4350703-A | β-Lactam antibacterial agents | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| US-4334070-A | NEUROLEPTIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1982-06-08 | — | — | US | disclosed |
| US-4088779-A | HYPOTENSIVE, ANTIFERTILITY | CIBA-GEIGY CORPORATION (US) | 1978-05-09 | — | — | US | disclosed |
| US-4077979-A | ANTIASTHMATIC | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-4077980-A | ANTIASTHMATIC | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12617777-B2 | GPR84 antagonists and uses thereof | GPR84, GPR88, GPR3 | CHRM2 169/4885CHRM4 137/4885CHRM5 193/4885 |
| US-20250223292-A1 | COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE | ATR, MAP3K20, CHEK1 | CHRM2 4763/4885CHRM4 4752/4885CHRM5 4703/4885 |
| US-20140357711-A1 | Amooranin Compounds and Analogs Thereof and Related Methods of Use | CYP27A1, OAT, AOX1 | CHRM2 567/4885CHRM4 421/4885CHRM5 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.