Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1534753 | 0.81 | TAAR1 (0.32) | — | |
| SCHEMBL2173845 | 0.81 | — | — | |
| SCHEMBL9919833 | 0.81 | OPRM1 (0.35) | ALDH1A1 | |
| SCHEMBL19128118 | 0.79 | CYP1A2 (0.45) | — | |
| SCHEMBL25365005 | 0.76 | MMP13 (0.34) | PGRALDH1A1 | |
| SCHEMBL29523581 | 0.76 | MMP13 (0.34) | PGRALDH1A1 | |
| SCHEMBL28612850 | 0.76 | GAA (0.34) | — | |
| SCHEMBL19183292 | 0.76 | SLC6A4 (0.30) | — | |
| SCHEMBL1534614 | 0.75 | CA1 (0.38) | — | |
| SCHEMBL25355763 | 0.75 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100261766-A1 | Phenyl-Oxetanyl-Derivatives | NOVARTIS AG (CH) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261766-A1 | Phenyl-Oxetanyl-Derivatives | SSB, OAT, OTC | HDAC6 1794/4885KIF11 4862/4885PGR 1483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.