SCHEMBL13089448

SCHEMBL13089448

CC(C)O[Si](C)(CC[Si](C)(Oc1ccccc1)Oc1ccccc1)OC(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
MTNR1A P48039 4/20 0.33
MTNR1B P49286 4/20 0.33
MAOA P21397 1/20 0.33
PTGS1 P23219 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
ALOX12 P18054 1/20 0.33
CA4 P22748 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
GAA P10253 1/20 0.31
KDM4E B2RXH2 1/20 0.31
VCP P55072 1/20 0.31
KCNA3 P22001 1/20 0.30
ADRB2 P07550 1/20 0.30
ADRB1 P08588 1/20 0.30
CYP2D6 P10635 1/20 0.30
ADRB3 P13945 1/20 0.30
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705837 0.86 CA4 (0.42) LMNAMTNR1AMTNR1BALDH1A1CA4
SCHEMBL13089371 0.85 LMNA (0.36) LMNAMTNR1AMTNR1BMAOAPTGS1
SCHEMBL13089423 0.80 CA4 (0.37) LMNAMTNR1AMTNR1BALDH1A1CA4
SCHEMBL705384 0.78 KCNA3 (0.41) LMNACA4KCNA3TSHRLTA4H
SCHEMBL704371 0.78 KCNA3 (0.41) LMNACA4KCNA3TSHRLTA4H
SCHEMBL13089454 0.76
SCHEMBL1596973 0.76 LTA4H (0.39) MAOAALDH1A1MAPTALOX12CA4
SCHEMBL14191179 0.75 HDAC3 (0.39) LMNAMTNR1AMTNR1BCA4KCNA3
SCHEMBL706567 0.74
SCHEMBL13089242 0.74 LMNA (0.36) LMNAMTNR1AMTNR1BMAOAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100261925-A1 METHOD FOR PRODUCING SILICON COMPOUND JSR CORPORATION (JP) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261925-A1 METHOD FOR PRODUCING SILICON COMPOUND GMNN, GEMIN5, SEPTIN7 LMNA 4134/4885MTNR1A 4868/4885MTNR1B 4820/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.