SCHEMBL1309364

SCHEMBL1309364

Brc1ccc2c(c1)Cc1cccc(Br)c1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 1/20 0.43
TDP2 O95551 2/20 0.42
SLC6A2 P23975 1/20 0.41
HTR2A P28223 1/20 0.41
HTR2C P28335 1/20 0.41
SLC6A4 P31645 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
TRPA1 O75762 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CHEK2 O96017 1/20 0.37
ROS1 P08922 1/20 0.37
MARK3 P27448 1/20 0.37
LTK P29376 1/20 0.37
FLT4 P35916 1/20 0.37
KDR P35968 1/20 0.37
MINK1 Q8N4C8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25929517 0.82 METAP1 (0.41) METAP1TDP2HTR2AHTR2CCA1
SCHEMBL30430068 0.80 MAOA (0.46) TDP2CA1CA2TRPA1TDP1
SCHEMBL789190 0.80 MAOA (0.46) TDP2CA1CA2TRPA1TDP1
SCHEMBL19494737 0.79 MAOA (0.45) CA1CA2TDP1L3MBTL1LTK
SCHEMBL15048544 0.78 METAP1 (0.41) METAP1TDP2SLC6A2HTR2AHTR2C
SCHEMBL12213268 0.77 CYP3A4 (0.43) TDP2SLC6A2HTR2AHTR2CSLC6A4
SCHEMBL29376113 0.77 METAP1 (0.57) METAP1TDP2CA1CA2CA4
SCHEMBL28126153 0.77 METAP1 (0.57) METAP1TDP2CA1CA2CA4
SCHEMBL40823 0.77 METAP1 (0.57) METAP1TDP2CA1CA2CA4
SCHEMBL17852135 0.76 TSHR (0.38) SLC6A2HTR2AHTR2CSLC6A4TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2349965-B1 2,5-LINKED POLYFLUORENES FOR OPTOELECTRONIC DEVICES BOE TECHNOLOGY GROUP CO LTD (CN) 2017-01-25 EP disclosed
US-8052892-B2 2,5-linked polyfluorenes for optoelectronic devices GENERAL ELECTRIC COMPANY (US) 2011-11-08 US disclosed
CN-102186800-A 2,5-linked polyfluorenes for optoelectronic devices GEN ELECTRIC 2011-09-14 CN disclosed
US-7968004-B2 2,5-linked polyfluorenes for optoelectronic devices GENERAL ELECTRIC COMPANY (US) 2011-06-28 US disclosed
US-7731866-B2 2,5-linked polyfluorenes for optoelectronic devices GENERAL ELECTRIC COMPANY (US) 2010-06-08 US disclosed
US-20100093968-A1 2,5-LINKED POLYFLUORENES FOR OPTOELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2010-04-15 US disclosed
US-20100093967-A1 2,5-LINKED POLYFLUORENES FOR OPTOELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2010-04-15 US disclosed
US-20100092801-A1 2,5-LINKED POLYFLUORENES FOR OPTOELECTRONIC DEVICES GENERAL ELECTRIC COMPANY (US) 2010-04-15 US disclosed
US-7635792-B1 2,5-linked polyfluorenes for optoelectronic devices GENERAL ELECTRIC COMPANY (US) 2009-12-22 US disclosed