Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30430068 | 1.00 | MAOA (0.46) | MAOAPOLBHTR2BALDH1A1MAPT | |
| SCHEMBL19494737 | 0.98 | MAOA (0.45) | MAOAPOLBHTR2BALDH1A1MAPT | |
| SCHEMBL18156795 | 0.88 | MAOA (0.43) | MAOAPOLBHTR2BALDH1A1MAPT | |
| SCHEMBL28096155 | 0.84 | MAOA (0.61) | MAOAPOLBALDH1A1MAPTKDM4E | |
| SCHEMBL12213268 | 0.84 | CYP3A4 (0.43) | MAOAALDH1A1MAPTDRD2DRD4 | |
| SCHEMBL16451424 | 0.83 | CES1 (0.46) | MAOAALDH1A1CES1MAPK1CA1 | |
| SCHEMBL28004757 | 0.81 | MAOA (0.54) | MAOAPOLBHTR2BALDH1A1MAPT | |
| SCHEMBL21703801 | 0.81 | PNMT (0.41) | MAOAPOLBHTR2BALDH1A1MAPT | |
| SCHEMBL1309364 | 0.80 | METAP1 (0.43) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL20222295 | 0.80 | LMNA (0.38) | MAOAPOLBHTR2BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104151130-B | A kind of method preparing high purity 4-bromine fluorenes | VALIANT Co.,Ltd. (CN) | 2016-04-06 | — | — | CN | claimed |
| CN-104151130-A | Novel method for preparing high-purity 4-bromofluorene | YANTAI VALIANT FINE CHEMICALS CO LTD | 2014-11-19 | — | — | CN | claimed |
| US-7473813-B2 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2009-01-06 | — | — | US | claimed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | claimed |
| CN-120058770-A | Aryl silicon modified spiro organic photoelectric functional material and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-120058771-A | Aryl silicon modified fluorene organic photoelectric functional material and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-120058771-A | Aryl silicon modified fluorene organic photoelectric functional material and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-119409865-B | Macromolecular light conversion agent, preparation method thereof and photovoltaic packaging light conversion adhesive film | 苏州易昇光学材料股份有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119409865-A | Macromolecular light conversion agent, preparation method thereof and photovoltaic packaging light conversion adhesive film | 苏州易昇光学材料股份有限公司 | 2025-02-11 | — | — | CN | disclosed |
| US-20240196746-A1 | ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2024-06-13 | — | — | US | disclosed |
| CN-114891032-B | Monoboro derivative based on fluorene-based aniline fusion donor, preparation and application thereof | 华中科技大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-113248392-B | Material for organic electroluminescent device | 默克专利有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | MARIN VLADIMIR | 2007-01-18 | — | — | US | disclosed |
| WO-2006137818-A1 | CATALYST COMPONENTS AND THEIR USE IN THE POLYMERIZATION OF OLEFINS | FINA TECHNOLOGY, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-7094938-B1 | Process for the preparation of substituted fluorenes | FINA TECHNOLOGY, INC. (US) | 2006-08-22 | — | — | US | disclosed |
| WO-2006065809-A2 | HETEROATOM BRIDGED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-06-22 | — | — | WO | disclosed |
| US-20050148460-A1 | Catalyst components and their use in the polymerization of olefins | FINA TECHNOLOGY, INC. | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015946-A1 | Process for the preparation of substituted fluorenes | TFDP2, ZKSCAN2, MDM4 | MAOA 675/4885POLB 486/4885HTR2B 1664/4885 |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | MAOA 958/4885POLB 2658/4885HTR2B 1802/4885 |
| US-20050148460-A1 | Catalyst components and their use in the polymerization of olefins | NPY5R, SSTR5, FGR | MAOA 143/4885POLB 210/4885HTR2B 145/4885 |
| US-20240196746-A1 | ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS | OR10J3, OR51E2, OCIAD2 | MAOA 328/4885POLB 2047/4885HTR2B 2796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.