Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120191 | 0.80 | MAOA (0.47) | TDP2TDP1L3MBTL1ALDH1A1MAOA | |
| SCHEMBL1309364 | 0.78 | METAP1 (0.43) | METAP1TDP2TDP1L3MBTL1SLC6A2 | |
| SCHEMBL15453499 | 0.72 | ALDH1A1 (0.45) | METAP1TDP2GSK3BTDP1L3MBTL1 | |
| SCHEMBL11808850 | 0.71 | METAP1 (0.47) | METAP1TDP2GSK3BERN1ALDH1A1 | |
| SCHEMBL29376113 | 0.71 | METAP1 (0.57) | METAP1TDP2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL40823 | 0.71 | METAP1 (0.57) | METAP1TDP2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL28126153 | 0.71 | METAP1 (0.57) | METAP1TDP2TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL29780658 | 0.70 | ALDH1A1 (0.59) | METAP1TDP2TDP1L3MBTL1SLC6A2 | |
| SCHEMBL29466104 | 0.70 | ALDH1A1 (0.59) | METAP1TDP2TDP1L3MBTL1SLC6A2 | |
| SCHEMBL415882 | 0.70 | ALDH1A1 (0.59) | METAP1TDP2TDP1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471035-B1 | Two-photon absorbing arylamine-endcapped and dialkylfluorene-bridged benzobisthiazole compounds with high oleophilicity | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2013-06-25 | — | — | US | disclosed |