Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095998 | 0.80 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MRGPRX4L3MBTL1 | |
| SCHEMBL3096002 | 0.80 | NR4A1 (0.59) | NR4A1NR4A2NR4A3MRGPRX4L3MBTL1 | |
| SCHEMBL3102966 | 0.79 | KCNQ3 (0.40) | NR4A1NR4A2NR4A3MRGPRX4L3MBTL1 | |
| SCHEMBL3102969 | 0.79 | KCNQ3 (0.40) | NR4A1NR4A2NR4A3MRGPRX4L3MBTL1 | |
| SCHEMBL31477055 | 0.76 | TRPV4 (0.42) | NR4A1NR4A2NR4A3MRGPRX4PTPN1 | |
| SCHEMBL934659 | 0.73 | TRPV4 (0.48) | MRGPRX4PTPN1L3MBTL1MLYCDTRPV4 | |
| SCHEMBL29456932 | 0.73 | TRPV4 (0.48) | MRGPRX4PTPN1L3MBTL1MLYCDTRPV4 | |
| SCHEMBL1317978 | 0.72 | MAPK1 (0.59) | PTPN1L3MBTL1TRPV4 | |
| SCHEMBL970954 | 0.71 | NR4A1 (0.50) | NR4A1NR4A2NR4A3PTPN1 | |
| SCHEMBL970955 | 0.71 | NR4A1 (0.50) | NR4A1NR4A2NR4A3PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318768-B2 | Bronchodilating alpha, beta-unsaturated isoquinoline amides | RESPIRATORIUS AB (SE) | 2012-11-27 | — | — | US | disclosed |
| US-8318768-B2 | Bronchodilating alpha, beta-unsaturated isoquinoline amides | RESPIRATORIUS AB (SE) | 2012-11-27 | — | — | US | disclosed |
| US-20100256101-A1 | NOVEL BRONCHODILATING ALPHA, BETA-UNSATURATED ISOQUINOLINE AMIDES | ARCEDE PHARMA AB (SE) | 2010-10-07 | — | — | US | disclosed |
| US-20100256101-A1 | NOVEL BRONCHODILATING ALPHA, BETA-UNSATURATED ISOQUINOLINE AMIDES | ARCEDE PHARMA AB (SE) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256101-A1 | NOVEL BRONCHODILATING ALPHA, BETA-UNSATURATED ISOQUINOLINE AMIDES | PTGIS, ADRB2, ADRB1 | NR4A1 1156/4885NR4A2 1706/4885NR4A3 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.