Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13096709 | 0.94 | EGFR (0.39) | SMN1; SMN2PKMEGFRTRPA1HTT | |
| SCHEMBL13096703 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2PKMEGFRTRPA1HTT | |
| SCHEMBL13106221 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2PKMEGFRTRPA1HTT | |
| SCHEMBL3092171 | 0.86 | ALDH1A1 (0.43) | SMN1; SMN2PKMEGFRHTTMAPT | |
| SCHEMBL3092175 | 0.86 | ALDH1A1 (0.43) | SMN1; SMN2PKMEGFRHTTMAPT | |
| SCHEMBL13096699 | 0.86 | EGFR (0.47) | SMN1; SMN2EGFRHTTMAPTSTAT3 | |
| SCHEMBL3100912 | 0.80 | L3MBTL1 (0.42) | SMN1; SMN2EGFRHTTMAPTSTAT3 | |
| SCHEMBL13096834 | 0.79 | L3MBTL1 (0.38) | SMN1; SMN2EGFRHTTMAPTSTAT3 | |
| SCHEMBL3086837 | 0.78 | L3MBTL1 (0.43) | SMN1; SMN2EGFRHTTMAPTSTAT3 | |
| SCHEMBL3086836 | 0.78 | L3MBTL1 (0.43) | SMN1; SMN2EGFRHTTMAPTSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | SMN1; SMN2 4848/4885PKM 1034/4885EGFR 4831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.