Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609739 | 0.87 | APAF1 (0.44) | APAF1TERTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL30165715 | 0.84 | KMT2A (0.50) | CASP1KDM4ELMNAPOLBCASP6 | |
| SCHEMBL146313 | 0.84 | KMT2A (0.50) | CASP1KDM4ELMNAPOLBCASP6 | |
| Hydrochloric Acid SCHEMBL40555 | 0.82 | MAPT (0.50) | CASP1KDM4ELMNAPOLBCASP6 | |
| Iodide SCHEMBL11279046 | 0.82 | KMT2A (0.48) | CASP1KDM4ELMNAPOLBCASP6 | |
| SCHEMBL13097886 | 0.81 | APAF1 (0.40) | APAF1TERTCASP1KDM4EPOLB | |
| Tolonium SCHEMBL2626791 | 0.81 | APAF1 (0.66) | APAF1TERTKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL12620639 | 0.81 | KDM4E (0.43) | CASP1KDM4ELMNAPOLBCASP6 | |
| Tolonium SCHEMBL30495506 | 0.80 | APAF1 (0.64) | APAF1TERTKDM4ESMN1; SMN2MEN1 | |
| Tolonium SCHEMBL122592 | 0.80 | APAF1 (0.64) | APAF1TERTKDM4ESMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256125-A1 | USE OF IMPROVED TOLUIDINE BLUE IN PHOTODYNAMIC THERAPY | ZILA PHARMACEUTICALS, INC. (US) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256125-A1 | USE OF IMPROVED TOLUIDINE BLUE IN PHOTODYNAMIC THERAPY | TET1, KDM2B, KDM5B | APAF1 2736/4885TERT 228/4885CASP1 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.