Hydrochloric Acid

Hydrochloric Acid

SCHEMBL40555

Nc1ccc2nc3ccc(N)cc3[s+]c2c1.[Cl-]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.48
ACHE known ✓ P22303 1/20 0.48
SLC6A2 known ✓ P23975 1/20 0.48
SLC6A3 known ✓ Q01959 1/20 0.48
MAPT P10636 4/20 0.50
HTT P42858 3/20 0.50
KDM4E B2RXH2 3/20 0.50
ATM Q13315 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
HSD17B10 Q99714 1/20 0.50
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
LMNA P02545 2/20 0.48
F2 P00734 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL146313 0.98 KMT2A (0.50) MAPTHTTKDM4EATMSMN1; SMN2
SCHEMBL30165715 0.98 KMT2A (0.50) MAPTHTTKDM4EATMSMN1; SMN2
Iodide SCHEMBL11279046 0.95 KMT2A (0.48) MAPTHTTKDM4EATMSMN1; SMN2
SCHEMBL12273001 0.88 HTR3A (0.48) MAPTHTTKDM4EATMSMN1; SMN2
Acetic Acid SCHEMBL755555 0.87 NQO2 (0.42) MAPTHTTKDM4EATMSMN1; SMN2
Iodide SCHEMBL12813166 0.86 HTR3A (0.47) MAPTHTTKDM4EATMSMN1; SMN2
SCHEMBL11281816 0.86 ALDH1A1 (0.44) MAPTHTTKDM4EATMSMN1; SMN2
SCHEMBL12620639 0.86 KDM4E (0.43) MAPTHTTKDM4EATMSMN1; SMN2
Iodide SCHEMBL12813168 0.85 HTR3A (0.46) MAPTHTTKDM4EATMSMN1; SMN2
Hydrochloric Acid SCHEMBL333986 0.84 KDM4E (0.39) MAPTHTTKDM4EATMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13573 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122071727-A Preparation method of chiral carbonyl-containing compound 北京化工大学 2026-05-22 CN claimed
CN-116845254-B Oxygen reduction catalyst of polyaniline conductive polymer coupled with carbon nano tube/covalent organic framework compound, and preparation method and application thereof 曲阜师范大学 2026-05-19 CN claimed
US-12605484-B2 Two-component system for the therapeutic treatment of skin lesions and production method thereof DTECH - SOCIETÀ A RESPONSABILITÀ LIMITATA (IT) 2026-04-21 US claimed
EP-4710943-A2 TRANSFECTION COMPLEXES AND METHODS OF USING THE SAME Molecular Transfer, Inc. (US) 2026-03-18 EP claimed
US-12569371-B2 Sterilization of medical dressings with enhanced antimicrobial properties HYDROFERA, LLC (US) 2026-03-10 US claimed
EP-4692774-A1 ELECTROCHEMICAL NUCLEIC ACID DETECTION SENSING ELEMENT AND ELECTROCHEMICAL NUCLEIC ACID DETECTION METHOD BASED ON RPA AND CRISPR/CAS Suzhou Zhong Ke Su Jing Biotechnology Co., Ltd. (CN) 2026-02-11 EP claimed
EP-4692776-A1 CRISPR/CAS-BASED ELECTROCHEMICAL NUCLEIC ACID DETECTION SENSING ELEMENT AND DETECTION METHOD Suzhou Zhong Ke Su Jing Biotechnology Co., Ltd. (CN) 2026-02-11 EP claimed
US-12540348-B2 Device and methods of using device for detection of aminoacidopathies UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2026-02-03 US claimed
EP-4649308-A2 APTAMER-BASED ANALYTE MONITORING SYSTEM Biolinq, Inc. (US) 2025-11-19 EP claimed
WO-2025233674-A1 ANTIMICROBIAL COMPOSITIONS: METHODS OF MAKING AND USING THE SAME ZONOVA TECHNOLOGIES LTD (GB) 2025-11-13 WO claimed
US-4232552-A THERMOCHROMISM, DISPOSABLE THERMOMETERS AKZONA INCORPORATED (US) 1980-11-11 US claimed
US-4224125-A Enzyme electrode MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1980-09-23 US claimed
US-4190705-A ELECTROLYTE SOLUTION CONTAINS PHOTOREDUCIBLE DYESTUFF AND REDOX COUPLE OF METALS SHELL OIL COMPANY (US) 1980-02-26 US claimed
US-4176026-A Process for catalytic photo-oxidation of water NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1979-11-27 US claimed
US-4169811-A DYE, ALKYLINE MATERIAL, REDUCING AGENT MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1979-10-02 US claimed
EP-0002321-A2 Photopolymerisable elements and a process for the production of printing plates therefrom BEXFORD LIMITED (GB) 1979-06-13 EP claimed
US-4141688-A THIAZINE, OXAZINE, OR AZINE DYE INDICATOR MILES LABORATORIES, INC. (US) 1979-02-27 US claimed
US-4052536-A THIAZINE DYE, RHODAMINE 6G, CSA-28 THE TRUSTEES OF BOSTON UNIVERSITY (US) 1977-10-04 US claimed
US-4003892-A Method of separating thionine and its N-methyl derivatives from each other SERVA-ENTWICKLUNGSLABOR V. GROTHE & CO. (DT) 1977-01-18 US claimed
US-3989542-A Photogalvanic device EXXON RESEARCH AND ENGINEERING COMPANY (US) 1976-11-02 US claimed