Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NCK1 | P16333 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146313 | 0.88 | KMT2A (0.50) | KDM4ELMNAPOLBCASP6MAPT | |
| SCHEMBL30165715 | 0.88 | KMT2A (0.50) | KDM4ELMNAPOLBCASP6MAPT | |
| Iodide SCHEMBL11279046 | 0.86 | KMT2A (0.48) | KDM4ELMNAPOLBCASP6MAPT | |
| Hydrochloric Acid SCHEMBL40555 | 0.86 | MAPT (0.50) | KDM4ELMNAPOLBCASP6MAPT | |
| SCHEMBL9609739 | 0.81 | APAF1 (0.44) | KDM4ENCK1BACE1NQO2MAPT | |
| SCHEMBL13097884 | 0.81 | APAF1 (0.44) | KDM4ELMNAPOLBCASP6NQO2 | |
| SCHEMBL12273001 | 0.79 | HTR3A (0.48) | KDM4ELMNAPOLBCASP6NQO2 | |
| Acetic Acid SCHEMBL755557 | 0.79 | CHEK1 (0.41) | KDM4ELMNAPOLBCASP6NQO2 | |
| Acetic Acid SCHEMBL755555 | 0.79 | NQO2 (0.42) | KDM4ELMNAPOLBCASP6NQO2 | |
| Iodide SCHEMBL12813166 | 0.78 | HTR3A (0.47) | KDM4ELMNAPOLBCASP6NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160248099-A1 | OXYGEN REDUCTION CATALYSTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2016-08-25 | — | — | US | disclosed |
| US-7951607-B2 | Compositions and methods for detecting nerve agents | UNIVERSITY OF WYOMING (US) | 2011-05-31 | — | — | US | disclosed |
| US-20100130757-A1 | COMPOSITIONS AND METHODS FOR DETECTING NERVE AGENTS | UNIVERSITY OF WYOMING (US) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130757-A1 | COMPOSITIONS AND METHODS FOR DETECTING NERVE AGENTS | PHOSPHO1, NCS1, GAP43 | KDM4E 1627/4885LMNA 1028/4885POLB 832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.