Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310500 | 0.79 | KMT2A (0.60) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL1310955 | 0.78 | KMT2A (0.49) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL1325020 | 0.74 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL14972752 | 0.73 | HSP90AA1 (0.49) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL1310328 | 0.72 | KMT2A (0.55) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL1311593 | 0.71 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL14972764 | 0.71 | KMT2A (0.66) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL14972763 | 0.71 | KMT2A (0.66) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL1308721 | 0.70 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1ALDH1A1GAAMAPT | |
| SCHEMBL1310049 | 0.70 | ALDH1A1 (0.45) | ALDH1A1GAAMAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846125-B2 | Enaminocarbonyl compounds and their use | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2014-09-30 | — | — | US | disclosed |
| EP-2391614-B1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INST CHEMII ORGANICZNEJ POLSKA AKADEMIA NAUK (PL) | 2013-05-29 | — | — | EP | disclosed |
| EP-2391614-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | Instytut Chemii Organicznej, Polska Akademia Nauk (PL) | 2011-12-07 | — | — | EP | disclosed |
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2011-11-10 | — | — | US | disclosed |
| WO-2010087727-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | TAS2R42, TAS2R41, TAS2R1 | HSP90AA1 4418/4885HSP90AB1 4303/4885ALDH1A1 1125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.