Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310500 | 0.86 | KMT2A (0.60) | KMT2AHSP90AA1HSP90AB1TAAR1ALDH1A1 | |
| SCHEMBL1310955 | 0.85 | KMT2A (0.49) | KMT2AHSP90AA1HSP90AB1ALDH1A1GAA | |
| SCHEMBL1310264 | 0.82 | ALDH1A1 (0.65) | KMT2AHSP90AA1HSP90AB1ALDH1A1GAA | |
| SCHEMBL14972763 | 0.78 | KMT2A (0.66) | KMT2AHSP90AA1HSP90AB1TAAR1ALDH1A1 | |
| SCHEMBL14972764 | 0.78 | KMT2A (0.66) | KMT2AHSP90AA1HSP90AB1TAAR1ALDH1A1 | |
| SCHEMBL1311373 | 0.77 | HSP90AA1 (0.73) | KMT2AHSP90AA1HSP90AB1TAAR1ALDH1A1 | |
| SCHEMBL13652557 | 0.77 | HSP90AA1 (0.73) | KMT2AHSP90AA1HSP90AB1TAAR1ALDH1A1 | |
| SCHEMBL14972765 | 0.76 | CYP1A2 (0.45) | KMT2AHSP90AA1HSP90AB1ALDH1A1GAA | |
| SCHEMBL1325020 | 0.75 | HSP90AA1 (0.49) | KMT2AHSP90AA1HSP90AB1ALDH1A1GAA | |
| SCHEMBL1310048 | 0.72 | HSP90AA1 (0.50) | KMT2AHSP90AA1HSP90AB1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846125-B2 | Enaminocarbonyl compounds and their use | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2014-09-30 | — | — | US | disclosed |
| EP-2391614-B1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INST CHEMII ORGANICZNEJ POLSKA AKADEMIA NAUK (PL) | 2013-05-29 | — | — | EP | disclosed |
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INSTYTUT CHEMII ORGANICZNEJ, POLSKA AKADEMIA NAUK (PL) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110274803-A1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | TAS2R42, TAS2R41, TAS2R1 | KMT2A 1458/4885HSP90AA1 4418/4885HSP90AB1 4303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.