Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988819 | 0.81 | KDM4E (0.51) | MTNR1AKDM4EL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL131009 | 0.77 | NR4A2 (0.40) | NR4A2MTNR1APLA2G2AKDM4ECYP1A2 | |
| SCHEMBL7558686 | 0.74 | KDM4E (0.49) | MTNR1APLA2G2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL26882759 | 0.74 | KDM4E (0.57) | NR4A2PLA2G2AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL28655389 | 0.74 | PLA2G2A (0.55) | NR4A2MTNR1APLA2G2AKDM4ECYP1A2 | |
| SCHEMBL382822 | 0.73 | KDM4E (0.66) | NR4A2PLA2G2AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL130494 | 0.73 | CA12 (0.61) | KDM4ECYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2949877 | 0.72 | KDM4E (0.64) | NR4A2PLA2G2AKDM4ECYP1A2CYP2D6 | |
| SCHEMBL7988831 | 0.72 | MEN1 (0.48) | NR4A2KDM4ECYP1A2CYP2C19TDP1 | |
| SCHEMBL7985137 | 0.72 | WDR5 (0.51) | NR4A2KDM4ETDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300340-B1 | USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| US-6162822-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 2000-12-19 | — | — | US | disclosed |
| US-5854273-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 1998-12-29 | — | — | US | disclosed |