SCHEMBL13101034

SCHEMBL13101034

CC(C)C(=O)n1ccc(N)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.33
TSHR P16473 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
NOS1 P29475 1/20 0.32
ALDH1A1 P00352 4/20 0.32
NPC1 O15118 1/20 0.32
USP2 O75604 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ADORA1 P30542 2/20 0.31
PDE5A O76074 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1259719 0.80 BCHE (0.43) ALDH1A1ADORA1RIPK1
SCHEMBL3604417 0.78
SCHEMBL1044057 0.75
SCHEMBL4106091 0.75
SCHEMBL3240144 0.69 ELANE (0.37) MAPTALDH1A1NPC1USP2HPGD
SCHEMBL306662 0.69 HSP90AA1 (0.39) MEN1KMT2AMAP4K4
SCHEMBL13924793 0.67 KDM4C (0.40) MAPTL3MBTL1ALDH1A1HPGDALOX15
SCHEMBL6616368 0.65 SCN4A (0.40) TSHRL3MBTL1NOS1ALDH1A1MEN1
SCHEMBL1427041 0.64
SCHEMBL13271926 0.63 ALOX15 (0.36) ALDH1A1ALOX15SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8530646-B2 Oxazolidinone derivative having 7-membered hetero ring RESEARCH FOUNDATION ITSUU LABORATORY (JP) 2013-09-10 US disclosed
US-20100256355-A1 OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING Research Foundation ITSUU Laboratory and Shionogi & Co., Ltd. 2010-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256355-A1 OXAZOLIDINONE DERIVATIVE HAVING 7-MEMBERED HETERO RING NR0B2, NR0B1, NR2C2 MAPT 4696/4885TSHR 733/4885L3MBTL1 1838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.