Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102471 | 0.86 | L3MBTL1 (0.48) | MAPTALDH1A1HPGDPRMT5WDR77 | |
| SCHEMBL3407850 | 0.84 | ALDH1A1 (0.67) | MAPTALDH1A1EPHX2HPGDGPR52 | |
| SCHEMBL7262423 | 0.81 | ACACB (0.58) | PRMT5WDR77KDM4E | |
| SCHEMBL7257964 | 0.81 | RAB9A (0.51) | MAPTALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL536638 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2GAAHTT | |
| SCHEMBL29378002 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1SMN1; SMN2GAAHTT | |
| SCHEMBL5694862 | 0.77 | MEN1 (0.43) | MAPTALDH1A1LMNAGAANPSR1 | |
| SCHEMBL537946 | 0.77 | HPGD (0.56) | MAPTALDH1A1EPHX2HPGDGPR52 | |
| SCHEMBL284764 | 0.76 | SMN1; SMN2 (0.55) | ALDH1A1HPGDSMN1; SMN2LMNAGAA | |
| SCHEMBL27339335 | 0.76 | EPHX2 (0.61) | MAPTALDH1A1EPHX2HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130237507-A1 | Novel Amide Compounds | ASTRAZENECA AB INTELLECTUAL PROPERTY (GB) | 2013-09-12 | — | — | US | disclosed |
| US-20100256104-A1 | NOVEL AMIDE COMPOUNDS | ASTRAZENECA R&D (SE) | 2010-10-07 | — | — | US | disclosed |
| US-20100256104-A1 | NOVEL AMIDE COMPOUNDS | ASTRAZENECA R&D (SE) | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256104-A1 | NOVEL AMIDE COMPOUNDS | H1-4, H1-3, H1-5 | MAPT 3420/4885ALDH1A1 1751/4885EPHX2 2036/4885 |
| US-20130237507-A1 | Novel Amide Compounds | H1-4, H1-3, H1-5 | MAPT 3448/4885ALDH1A1 1605/4885EPHX2 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.