Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311350 | 1.00 | KMT2A (0.38) | KMT2AMEN1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL1310852 | 0.81 | SMN1; SMN2 (0.41) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1310210 | 0.81 | SMN1; SMN2 (0.40) | KMT2AMEN1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL12112903 | 0.71 | KMT2A (0.37) | KMT2AMEN1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL1315257 | 0.69 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL1313304 | 0.69 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL1311333 | 0.68 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL1310591 | 0.68 | TLR9 (0.32) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1311024 | 0.67 | TLR9 (0.32) | — | |
| SCHEMBL1336968 | 0.66 | LMNA (0.43) | KMT2AMEN1ALDH1A1CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275638-A1 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (SE) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275638-A1 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS | ADIPOR2, GPR119, ADIPOR1 | KMT2A 2294/4885MEN1 3508/4885ALDH1A1 1875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.