Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310044 | 1.00 | MTNR1A (0.47) | MTNR1AMTNR1BKDM4ETRPV1CNR1 | |
| SCHEMBL1311781 | 0.96 | KDM4E (0.49) | MTNR1AMTNR1BKDM4EHPGDHSD17B10 | |
| SCHEMBL12114691 | 0.79 | MTNR1A (0.40) | MTNR1AMTNR1B | |
| SCHEMBL1309784 | 0.78 | MTNR1A (0.60) | MTNR1AMTNR1BKDM4EHSD17B10 | |
| SCHEMBL8822710 | 0.69 | MTNR1A (0.46) | MTNR1AMTNR1BKDM4EHPGDHSD17B10 | |
| SCHEMBL1309768 | 0.68 | MTNR1A (0.57) | MTNR1AMTNR1BKDM4EHPGDHSD17B10 | |
| SCHEMBL29178467 | 0.62 | THRA (0.49) | TRPV1 | |
| SCHEMBL12360869 | 0.62 | FAAH (1.00) | TRPV1CNR1HPGDFAAH | |
| SCHEMBL25350370 | 0.62 | FAAH (0.77) | TRPV1CNR1HPGDFAAH | |
| SCHEMBL2089790 | 0.62 | FAAH (0.77) | TRPV1CNR1HPGDFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053462-B2 | Indole derivative and application thereof | SOMEI MASANORI | 2011-11-08 | — | — | US | disclosed |
| US-20070197629-A1 | Indole derivative and application thereof | SOMEI MASANORI | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197629-A1 | Indole derivative and application thereof | ARL1, IDO1, AIPL1 | MTNR1A 143/4885MTNR1B 287/4885KDM4E 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.