Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311213 | 0.91 | ALDH1A1 (0.38) | ALDH1A1CYP19A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL1310637 | 0.90 | ALDH1A1 (0.37) | ALDH1A1CYP19A1LMNAMAPTMAPK1 | |
| SCHEMBL1311247 | 0.89 | ALDH1A1 (0.45) | ALDH1A1CYP19A1LMNAKCNA5CYP3A4 | |
| Hydrochloric Acid SCHEMBL1312450 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP19A1LMNAKCNA5CYP3A4 | |
| SCHEMBL1310792 | 0.86 | CYP19A1 (0.33) | ALDH1A1CYP19A1LMNAMAPTMAPK1 | |
| SCHEMBL1310383 | 0.81 | CYP19A1 (0.42) | ALDH1A1CYP19A1LMNAMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL1312267 | 0.80 | ALDH1A1 (0.41) | ALDH1A1CYP19A1LMNAMAPTMAPK1 | |
| SCHEMBL1310507 | 0.78 | ERCC1 (0.36) | ALDH1A1LMNACYP3A4L3MBTL1ERCC1 | |
| Hydrochloric Acid SCHEMBL1311860 | 0.77 | ERCC1 (0.35) | ALDH1A1LMNACYP3A4L3MBTL1ERCC1 | |
| SCHEMBL1310603 | 0.75 | MMP8 (0.44) | ALDH1A1MAPTCYP3A4RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275638-A1 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (SE) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275638-A1 | PIPERAZINE DERIVATIVES AND THEIR USE AS LEPTIN RECEPTOR MODULATORS | ADIPOR2, GPR119, ADIPOR1 | ALDH1A1 1875/4885CYP19A1 1411/4885LMNA 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.