Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1311521 | 0.89 | KCNMA1 (0.50) | HCAR3HPGDHCAR2KCNMA1CLK1 | |
| SCHEMBL19848372 | 0.80 | MAPK14 (0.58) | HCAR3HPGDHCAR2MAPK14CLK1 | |
| SCHEMBL2069140 | 0.79 | HSD17B10 (0.50) | HCAR3HPGDHCAR2KMT2AMGAM | |
| SCHEMBL22781912 | 0.75 | MAPK14 (0.43) | HCAR3HPGDHCAR2MAPK14CLK1 | |
| SCHEMBL19911628 | 0.75 | HCAR3 (0.55) | HCAR3HPGDHCAR2MAPK14CLK1 | |
| SCHEMBL6155966 | 0.72 | GAA (0.49) | HPGDKCNMA1KMT2AMGAMAMY1A | |
| SCHEMBL20888878 | 0.72 | MAPK14 (0.39) | HCAR3HPGDHCAR2MAPK14KCNMA1 | |
| SCHEMBL1311460 | 0.71 | HCAR3 (0.49) | HCAR3HPGDHCAR2KCNMA1KMT2A | |
| SCHEMBL1312538 | 0.71 | HCAR3 (0.49) | HCAR3HPGDHCAR2KCNMA1KMT2A | |
| SCHEMBL19911626 | 0.71 | KMT2A (0.48) | HPGDKCNMA1KMT2AMGAMAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387568-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NeuroSearch A/S (DK) | 2011-11-23 | — | — | EP | claimed |
| US-20110275684-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NEUROSEARCH A/S (DK) | 2011-11-10 | — | — | US | claimed |
| US-8040036-B2 | Organic light emitting device and method for manufacturing the same | LG CHEM, LTD. (KR) | 2011-10-18 | — | — | US | claimed |
| WO-2010081898-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NEUROSEARCH A/S (DK) | 2010-07-22 | — | — | WO | claimed |
| EP-2387568-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NeuroSearch A/S (DK) | 2011-11-23 | — | — | EP | disclosed |
| US-20110275684-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NEUROSEARCH A/S (DK) | 2011-11-10 | — | — | US | disclosed |
| US-8040036-B2 | Organic light emitting device and method for manufacturing the same | LG CHEM, LTD. (KR) | 2011-10-18 | — | — | US | disclosed |
| WO-2010081898-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | NEUROSEARCH A/S (DK) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275684-A1 | NOVEL BENZOTRIAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF CNS DISORDERS | GABBR1, ABAT, GABBR2 | HCAR3 541/4885HPGD 2292/4885HCAR2 316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.