SCHEMBL13129145

SCHEMBL13129145

CCc1cc(Cc2cc(CC)c(NC(=O)CC(C)C)c(CC)c2)cc(CC)c1NC(=O)CC(C)C

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
MAPK14 Q16539 1/20 0.43
HPGD P15428 3/20 0.42
LMNA P02545 3/20 0.42
GAA P10253 2/20 0.42
KDM4E B2RXH2 2/20 0.40
TSHR P16473 1/20 0.40
CTSD P07339 1/20 0.40
ALDH1A1 P00352 2/20 0.39
ADORA1 P30542 1/20 0.39
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129139 0.92 ALDH1A1 (0.45) PTPN1SMN1; SMN2RAB9ANPC1MAPK14
SCHEMBL13129135 0.83 ALDH1A1 (0.54) PTPN1SMN1; SMN2RAB9ANPC1HPGD
SCHEMBL12284735 0.81 GAA (0.50) SMN1; SMN2HPGDLMNAGAATSHR
SCHEMBL12284741 0.80 SMN1; SMN2 (0.45) PTPN1SMN1; SMN2RAB9ANPC1MAPK14
SCHEMBL27734228 0.79 SMN1; SMN2 (0.57) PTPN1SMN1; SMN2RAB9ANPC1HPGD
SCHEMBL13129142 0.77 HPGD (0.50) RAB9AHPGDKDM4EALDH1A1ADORA1
SCHEMBL12284575 0.75 LMNA (0.50) SMN1; SMN2LMNAGAAALDH1A1
SCHEMBL12285484 0.74 EPHX2 (0.53) SMN1; SMN2RAB9ANPC1HPGDGAA
SCHEMBL14864150 0.74 HPGD (0.49) SMN1; SMN2RAB9ANPC1HPGDLMNA
SCHEMBL13129147 0.73 HPGD (0.48) SMN1; SMN2RAB9ANPC1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4253470-A1 CRYSTALLIZATION INHIBITOR FOR POLYOLEFIN RESIN, POLYOLEFIN RESIN COMPOSITION, MOLDED ARTICLE, METHOD FOR PRODUCING POLYOLEFIN RESIN COMPOSITION, AND METHOD FOR INHIBITING CRYSTALLIZATION OF POLYOLEFIN RESIN ADEKA CORPORATION (JP) 2023-10-04 EP disclosed
WO-2022114072-A1 CRYSTALLIZATION INHIBITOR FOR POLYOLEFIN RESIN, POLYOLEFIN RESIN COMPOSITION, MOLDED ARTICLE, METHOD FOR PRODUCING POLYOLEFIN RESIN COMPOSITION, AND METHOD FOR INHIBITING CRYSTALLIZATION OF POLYOLEFIN RESIN 株式会社ADEKA 2022-06-02 WO disclosed
US-8420721-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2013-04-16 US disclosed
US-20100240815-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-09-23 US disclosed