SCHEMBL12285477

SCHEMBL12285477

CCc1cc(Cc2cc(CC)c(NC(=O)c3ccccc3)c(CC)c2)cc(CC)c1NC(=O)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
ALDH1A1 P00352 2/20 0.54
KCNK3 O14649 2/20 0.50
KCNK9 Q9NPC2 2/20 0.50
LTC4S Q16873 1/20 0.50
HTT P42858 2/20 0.48
LMNA P02545 2/20 0.47
KMT2A Q03164 1/20 0.47
MAPT P10636 6/20 0.46
BCL2 P10415 2/20 0.44
MCL1 Q07820 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HPGD P15428 2/20 0.44
ALOX15 P16050 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
POLB P06746 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129140 0.92 KDM4E (0.50) KDM4EALDH1A1KCNK3KCNK9LTC4S
SCHEMBL1491944 0.84 ALDH1A1 (0.54) KDM4EALDH1A1KCNK3KCNK9HTT
SCHEMBL12284720 0.83 HTT (0.55) KDM4EALDH1A1KCNK3KCNK9LTC4S
Iodide SCHEMBL30758627 0.81 KDM4E (0.67) KDM4EALDH1A1KCNK3KCNK9HTT
SCHEMBL12285484 0.79 EPHX2 (0.53) KDM4EALDH1A1HTTKMT2AMAPT
SCHEMBL15014133 0.79 HTT (0.54) KDM4EALDH1A1HTTLMNAKMT2A
SCHEMBL13129151 0.78 LMNA (0.69) KCNK3KCNK9LTC4SHTTLMNA
SCHEMBL19426861 0.75 KDM4E (0.55) KDM4EALDH1A1KCNK3KCNK9HTT
SCHEMBL27872677 0.74 ALDH1A1 (0.68) KDM4EALDH1A1KCNK3KCNK9HTT
SCHEMBL13866793 0.74 CA5A (0.42) KDM4EALDH1A1HTTKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630693-B2 Small-cell polystyrene foams, and process for producing same INEOS STYROLUTION GROUP GMBH (DE) 2026-05-19 US disclosed
EP-4153668-B1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME INEOS STYROLUTION GROUP GMBH (DE) 2024-08-28 EP disclosed
US-20230227627-A1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME INEOS STYROLUTION GROUP GMBH (DE) 2023-07-20 US disclosed
US-8420721-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2013-04-16 US disclosed
US-8288462-B2 Polyolefin resin composition ADEKA CORPORATION (JP) 2012-10-16 US disclosed
US-20110218279-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2011-09-08 US disclosed
US-20100240815-A1 POLYOLEFIN RESIN COMPOSITION ADEKA CORPORATION (JP) 2010-09-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227627-A1 SMALL-CELL POLYSTYRENE FOAMS, AND PROCESS FOR PRODUCING SAME F12, FDFT1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 KDM4E 4244/4885ALDH1A1 2229/4885KCNK3 3544/4885
US-12630693-B2 Small-cell polystyrene foams, and process for producing same H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, CBR3 KDM4E 4306/4885ALDH1A1 2067/4885KCNK3 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.