SCHEMBL13129264

SCHEMBL13129264

c1ccc(-c2sc3cc(-c4ccc5c6ccccc6c6ccccc6c5c4)ccc3c2-c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.52
▸ ITGA4 P13612 2/20 0.43
▸ MEN1 O00255 2/20 0.42
▸ HSP90AA1 P07900 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ PAX8 Q06710 1/20 0.39
▸ LIMK1 P53667 1/20 0.38
▸ NAPEPLD Q6IQ20 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ PIK3CA P42336 1/20 0.35
▸ PI4KA P42356 1/20 0.35
▸ PI4KB Q9UBF8 1/20 0.35
▸ PTPN1 P18031 1/20 0.34
▸ ROCK1 Q13464 1/20 0.34
▸ UBE2N P61088 1/20 0.34
▸ ABCB1 P08183 1/20 0.33
▸ ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129258 0.90 L3MBTL1 (0.52) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL12296775 0.85 L3MBTL1 (0.46) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL12296773 0.83 L3MBTL1 (0.44) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL17190883 0.83 L3MBTL1 (0.46) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL12296776 0.82 L3MBTL1 (0.43) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL12011500 0.82 L3MBTL1 (0.43) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL12761614 0.81 L3MBTL1 (0.48) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL17190913 0.81 L3MBTL1 (0.45) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL18590855 0.80 L3MBTL1 (0.51) L3MBTL1ITGA4MEN1HSP90AA1KMT2A
SCHEMBL12761633 0.80 L3MBTL1 (0.47) L3MBTL1ITGA4MEN1HSP90AA1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 — — US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 — — US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 — — US disclosed
US-9705092-B2 Phosphorescent organic light emitting devices combined with hole transport material having high operating stability UNIVERSAL DISPLAY CORPORATION (US) 2017-07-11 — — US disclosed
US-9705092-B2 Phosphorescent organic light emitting devices combined with hole transport material having high operating stability UNIVERSAL DISPLAY CORPORATION (US) 2017-07-11 — — US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 — — US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 — — US disclosed
EP-3159333-A2 BENZO-FUSED THIOPHENE OR FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP Universal Display Corporation (US) 2017-04-26 — — EP disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 — — US disclosed
US-9577200-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-02-21 — — US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 — — US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 — — US disclosed
US-20130175510-A1 BENZO-FUSED THIOPHENE / TRIPHENYLENE HYBRID MATERIALS UNIVERSAL DISPLAY CORPORTION (US) 2013-07-11 — — US disclosed
US-20130175510-A1 BENZO-FUSED THIOPHENE / TRIPHENYLENE HYBRID MATERIALS UNIVERSAL DISPLAY CORPORTION (US) 2013-07-11 — — US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 — — US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 — — US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 — — US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 — — US disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 — — WO disclosed
WO-2009021126-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC L3MBTL1 828/4885ITGA4 4484/4885MEN1 1460/4885
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEC L3MBTL1 508/4885ITGA4 1799/4885MEN1 2239/4885
US-10374171-B2 Organic electroluminescent materials and devices TPR, EED, TEAD2 L3MBTL1 504/4885ITGA4 3326/4885MEN1 1998/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback