SCHEMBL13129258

SCHEMBL13129258

c1ccc(-c2sc3ccc(-c4ccc5c6ccccc6c6ccccc6c5c4)cc3c2-c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.52
▸ ITGA4 P13612 2/20 0.43
▸ HSP90AA1 P07900 3/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ ROCK1 Q13464 1/20 0.39
▸ PAX8 Q06710 1/20 0.39
▸ LIMK1 P53667 1/20 0.38
▸ HCRTR1 O43613 1/20 0.38
▸ PIM3 Q86V86 1/20 0.38
▸ NAPEPLD Q6IQ20 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ F9 P00740 1/20 0.36
▸ MC4R P32245 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13129264 0.90 L3MBTL1 (0.52) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL25059266 0.85 L3MBTL1 (0.48) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL13991415 0.82 L3MBTL1 (0.46) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL13991404 0.81 L3MBTL1 (0.45) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL22789803 0.80 LIMK1 (0.46) ROCK1LIMK1PIM3F9
SCHEMBL18590855 0.80 L3MBTL1 (0.51) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL1294397 0.80 L3MBTL1 (0.68) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL13991417 0.79 L3MBTL1 (0.43) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL13991409 0.79 CA12 (0.44) L3MBTL1ITGA4HSP90AA1MEN1KMT2A
SCHEMBL13991408 0.79 L3MBTL1 (0.43) L3MBTL1ITGA4HSP90AA1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710557-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2022-05-18 — — EP disclosed
US-20200395548-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PERFORMANCE MATERIALS GERMANY GMBH (DE) 2020-12-17 — — US disclosed
US-10374171-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 — — US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 — — US disclosed
US-9997727-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2018-06-12 — — US disclosed
US-9705092-B2 Phosphorescent organic light emitting devices combined with hole transport material having high operating stability UNIVERSAL DISPLAY CORPORATION (US) 2017-07-11 — — US disclosed
US-9705092-B2 Phosphorescent organic light emitting devices combined with hole transport material having high operating stability UNIVERSAL DISPLAY CORPORATION (US) 2017-07-11 — — US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 — — US disclosed
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-04-27 — — US disclosed
EP-3159333-A2 BENZO-FUSED THIOPHENE OR FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP Universal Display Corporation (US) 2017-04-26 — — EP disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 — — US disclosed
US-8822708-B2 Benzo-fused thiophene / triphenylene hybrid materials UNIVERSAL DISPLAY CORPORATION (US) 2014-09-02 — — US disclosed
US-20130175510-A1 BENZO-FUSED THIOPHENE / TRIPHENYLENE HYBRID MATERIALS UNIVERSAL DISPLAY CORPORTION (US) 2013-07-11 — — US disclosed
US-20130175510-A1 BENZO-FUSED THIOPHENE / TRIPHENYLENE HYBRID MATERIALS UNIVERSAL DISPLAY CORPORTION (US) 2013-07-11 — — US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 — — US disclosed
US-8367850-B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group UNIVERSAL DISPLAY CORPORATION (US) 2013-02-05 — — US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 — — US disclosed
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group UNIVERSAL DISPLAY CORPORATION (US) 2010-09-23 — — US disclosed
WO-2009021126-A9 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-09-11 — — WO disclosed
WO-2009021126-A2 BENZO-FUSED THIOPHENE OR BENZO-FUSED FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP UNIVERSAL DISPLAY CORPORATION (US) 2009-02-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100237334-A1 Benzo-Fused Thiophene or Bezon-Fused Furan Compounds Comprising a Triphenylene Group TFEB, BRD4, TEC L3MBTL1 828/4885ITGA4 4484/4885HSP90AA1 2837/4885
US-20170117489-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES TPR, EED, TEC L3MBTL1 508/4885ITGA4 1799/4885HSP90AA1 4486/4885
US-20200395548-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES TRMT1, EED, TEC L3MBTL1 2019/4885ITGA4 1507/4885HSP90AA1 3811/4885
US-10374171-B2 Organic electroluminescent materials and devices TPR, EED, TEAD2 L3MBTL1 504/4885ITGA4 3326/4885HSP90AA1 3988/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback