Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 8/20 | 0.38 |
| ▸ | LGALS7; LGALS7B | P47929 | 3/20 | 0.36 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | LGALS9 | O00182 | 3/20 | 0.36 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.33 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113910 | 0.86 | LGALS3 (0.43) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CD69 | |
| SCHEMBL13130299 | 0.83 | LGALS3 (0.42) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CD69 | |
| SCHEMBL13321918 | 0.80 | CD69 (0.41) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CD69 | |
| SCHEMBL16016954 | 0.78 | CD69 (0.43) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CD69 | |
| SCHEMBL13130296 | 0.76 | BDNF (0.46) | LGALS3LGALS7; LGALS7BLGALS1CD69 | |
| SCHEMBL25964076 | 0.76 | MAPK1 (0.41) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CD69 | |
| SCHEMBL21743003 | 0.75 | MAPK1 (0.39) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CD69 | |
| SCHEMBL14089003 | 0.73 | ALDH1A1 (0.48) | LGALS3CD69LGALS8LGALS4ALDH1A1 | |
| SCHEMBL14444723 | 0.71 | LMNA (0.34) | LGALS3LGALS7; LGALS7BLGALS1LGALS9ALDH1A1 | |
| SCHEMBL13994673 | 0.70 | MAPK1 (0.41) | LGALS3LGALS7; LGALS7BLGALS1LGALS9CD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100248260-A1 | GLYCOSAMINOGLYCAN-COATED PARTICLES AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-09-30 | — | — | US | disclosed |