SCHEMBL131333

SCHEMBL131333

c1cc(CC2CO2)ccc1CC1CO1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
ALDH1A1 P00352 4/20 0.37
TP53 P04637 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
HIF1A Q16665 1/20 0.37
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
HBB P68871 1/20 0.35
GLA P06280 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MGLL Q99685 2/20 0.34
GRM2 Q14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14063010 0.92 MGLL (0.38) MGLL
SCHEMBL13990310 0.92 MGLL (0.42) TDP1ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL5522519 0.88 ALOX5 (0.45) ALDH1A1SLC6A2SLC6A4SLC6A3
SCHEMBL13169323 0.88 TDP1 (0.32) TDP1ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL3065497 0.88 TP53 (0.39) TDP1ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL1499186 0.88 MAOB (0.42) ALDH1A1SLC6A4MEN1KMT2A
SCHEMBL1499381 0.88 IDO1 (0.41)
SCHEMBL19111959 0.88 MEN1 (0.41) TDP1ALDH1A1SMN1; SMN2GLAMEN1
SCHEMBL9089862 0.88 MEN1 (0.33) TDP1ALDH1A1TP53SMN1; SMN2CYP3A4
SCHEMBL5522518 0.88 MGLL (0.33) TDP1ALDH1A1TP53SMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 617 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080157023-A1 Hydrofluoroalkene, an iodocarbon, a lubricant and a metal stabilizer; automotive air conditioning systems HONEYWELL INTERNATIONAL INC 2008-07-03 US claimed
CN-1965049-A Stabilized trifluoroiodomethane compositions HONEYWELL INT INC (US) 2007-05-16 CN claimed
US-20060033072-A1 Stabilized trifluoroiodomethane compositions HONEYWELL INTERNATIONAL INC. (US) 2006-02-16 US claimed
JP-2220885-A None JP disclosed
JP-4135789-A None JP disclosed
EP-3858877-B1 POLYFUNCTIONAL VINYL AROMATIC COPOLYMER AND METHOD FOR MANUFACTURING SAME, COPOLYMER RUBBER OBTAINED THEREFROM, RUBBER COMPOSITION, RUBBER CROSSLINKED MATERIAL, AND TIRE MEMBER NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2026-05-27 EP disclosed
US-12617238-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
EP-4722000-A1 TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-04-08 EP disclosed
US-12589615-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2026-03-31 US disclosed
EP-4706987-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-03-11 EP disclosed
EP-4706982-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-03-11 EP disclosed
US-4977239-A FILTER MEDIA CASSELLA AKTIENGESELLSCHAFT (DE) 1990-12-11 US disclosed
JP-H02220885-A THERMAL COLOR MATERIAL KANZAKI PAPER MFG CO LTD 1990-09-04 JP disclosed
EP-0232519-B1 COPOLYMER, PROCESS FOR ITS PREPARATION AND ITS USE CASSELLA Aktiengesellschaft (DE) 1990-08-29 EP disclosed
EP-0376151-A2 Process for dyeing textile materials with pigment dyes HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-04 EP disclosed
EP-0363745-A2 Polybase, process for its preparation and its use CASSELLA Aktiengesellschaft (DE) 1990-04-18 EP disclosed
US-4810254-A Wet-fastness properties of sulphur dyestuffs dyeings on cellulose treated with poly-di-allyl-ammonium salt CASSELLA AKTIENGESELLSCHAFT (DE) 1989-03-07 US disclosed
EP-0277580-A2 Modification of the wet fastness of sulphur dyeings CASSELLA Aktiengesellschaft (DE) 1988-08-10 EP disclosed
US-4753999-A ADDITION POLYMER CONTAINING QUATERNARY AMMONIUM MONOMER, IMPROVES COLORFASTNESS OF DYES ON TEXTILES CASSELLA AKTIENGESELLSCHAFT (DE) 1988-06-28 US disclosed
EP-0232519-A2 Copolymer, process for its preparation and its use CASSELLA Aktiengesellschaft (DE) 1987-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12589615-B2 Pneumatic tire LBR, TERF2, TLN1 TDP1 1855/4885ALDH1A1 3840/4885TP53 3048/4885
US-12617238-B2 Pneumatic tire CCT4, CCT7, CCNE2 TDP1 3155/4885ALDH1A1 4505/4885TP53 2187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.