SCHEMBL1499381

SCHEMBL1499381

Fc1ccc(CC2CO2)cc1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
TAAR1 Q96RJ0 1/20 0.38
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
AGXT P21549 1/20 0.37
TRPA1 O75762 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14062723 0.94 MAOB (0.42) IDO1LOXL2
SCHEMBL131333 0.88 TDP1 (0.38)
SCHEMBL14063010 0.81 MGLL (0.38)
SCHEMBL9843341 0.81 MEN1 (0.39)
SCHEMBL13990310 0.81 MGLL (0.42)
SCHEMBL708540 0.81 MGLL (0.38)
SCHEMBL8803172 0.78 DRD4 (0.50) TAAR1POLB
SCHEMBL14062992 0.78 CHKA (0.35)
SCHEMBL1445116 0.77 MEN1 (0.41) IDO1TAAR1LMNAPOLBAGXT
SCHEMBL3065497 0.77 TP53 (0.39) TAAR1KDM4ELMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710159-A1 CATALYST COMPONENTS FOR PROPYLENE POLYMERIZATION W. R. Grace & Co. - Conn. (US) 2020-09-23 EP claimed
US-8344079-B2 Molar ratio modifications to larger polyolefin catalysts BASF CORPORATION (US) 2013-01-01 US claimed
JP-2011508053-A 2011-03-10 JP claimed
EP-2242776-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF Corporation (US) 2010-10-27 EP claimed
WO-2009088596-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF CATALYSTS LLC (US) 2009-07-16 WO claimed
US-20090171044-A1 MOLAR RATIO MODIFICATIONS TO LARGER POLYOLEFIN CATALYSTS BASF CATALYSTS LLC (US) 2009-07-02 US claimed
US-20260103548-A1 PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY W. R. GRACE & CO.-CONN. 2026-04-16 US disclosed
EP-3592783-B1 ELECTRON DONORS FOR ZIEGLER-NATTA PRECATALYST PREPARATION AND CATALYST SYSTEM FOR OLEFIN POLYMERIZATION GRACE W R & CO (US) 2025-11-12 EP disclosed
US-20250235842-A1 GAS-PHASE PROCESS FOR MAKING POLYPROPYLENE RANDOM COPOLYMERS W.R. GRACE & CO.-CONN (US) 2025-07-24 US disclosed
US-20250145745-A1 HIGH MFR POLYPROPYLENE FOR MELTBLOWN NONWOVEN APPLICATIONS W. R. GRACE & CO.-CONN. 2025-05-08 US disclosed
US-20250109220-A1 Olefin Polymerization Catalyst Comprising Magnesium, Titanium, an Epoxy Compound and an Internal Electron Donor, Such as a 1,2-Phenylene Dibenzoate-Based Compound W. R. GRACE & CO.-CONN. 2025-04-03 US disclosed
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization W. R. GRACE & CO.- CONN. (US) 2025-03-04 US disclosed
EP-4473023-A1 OLEFIN POLYMERIZATION CATALYST COMPRISING MAGNESIUM, TITANIUM, AN EPOXY COMPOUND AND AN INTERNAL ELECTRON DONOR, SUCH AS A 1,2-PHENYLENE DIBENZOATE-BASED COMPOUND W.R. GRACE & CO.-CONN. (US) 2024-12-11 EP disclosed
US-6130346-A ESTERIFICATION, CARBONATION, SULFONATION, ETHERIFICATION MITSUI CHEMICALS, INC. (JP) 2000-10-10 US disclosed
EP-0972776-A1 A phosphine sulfide, a manufacturing process therefor and a use thereof Mitsui Chemicals, Inc. (JP) 2000-01-19 EP disclosed
EP-0950649-A1 A process for preparing oxyalkylene derivatives in the presence of phosphine oxides Mitsui Chemicals, Inc. (JP) 1999-10-20 EP disclosed
US-4209447-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1980-06-24 US disclosed
US-4181664-A 2-AR-2-HALO OR SUBSTITUTED SULFONYLOXYMETHYL-4-R-1,3-DIOXOLANES, FOR MAKING FUNGICIDES AND BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1980-01-01 US disclosed
US-4139540-A FUNGICIDE, BACTERICIDE INTERMEDIATE JANSSEN PHARMACEUTICA N.V. (BE) 1979-02-13 US disclosed
US-4120869-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12240925-B2 Process for preparing solid catalyst components for olefin polymerization POF1B, PPOX, OGFOD1 IDO1 3468/4885LOXL2 4193/4885TAAR1 3916/4885
US-20260103548-A1 PROCESS FOR PRODUCING POLYPROPYLENE-ETHYLENE RANDOM COPOLYMER RESIN WITH SUSTAINABLE REACTOR OPERABILITY CCT4, PTGER1, TCP1 IDO1 3938/4885LOXL2 3032/4885TAAR1 1463/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.