Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.47 |
| ▸ | MMP9 | P14780 | 10/20 | 0.47 |
| ▸ | MMP8 | P22894 | 10/20 | 0.47 |
| ▸ | MMP13 | P45452 | 10/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16180807 | 1.00 | MMP2 (0.47) | MMP2MMP9MMP8MMP13DGAT1 | |
| SCHEMBL17776308 | 0.92 | DGAT1 (0.48) | MMP2MMP9MMP8MMP13DGAT1 | |
| SCHEMBL21537936 | 0.89 | DGAT1 (0.45) | MMP2MMP9MMP8MMP13DGAT1 | |
| SCHEMBL13139325 | 0.87 | MMP2 (0.47) | MMP2MMP9MMP8MMP13DGAT1 | |
| SCHEMBL24276657 | 0.84 | DGAT1 (0.53) | MMP2MMP9MMP8MMP13DGAT1 | |
| SCHEMBL18768971 | 0.84 | DGAT1 (0.53) | MMP2MMP9MMP8MMP13DGAT1 | |
| SCHEMBL17300275 | 0.83 | DRD2 (0.47) | MMP2MMP9MMP8MMP13DRD2 | |
| SCHEMBL17776309 | 0.83 | CSNK2A1 (0.41) | MMP2MMP9MMP8MMP13DGAT1 | |
| SCHEMBL27269271 | 0.83 | GBA1 (0.39) | MMP2MMP9MMP8MMP13DGAT1 | |
| SCHEMBL24450930 | 0.82 | DGAT1 (0.39) | MMP2MMP9MMP8MMP13DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130216475-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | GENENTECH, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-8435488-B2 | Methods and compositions for protein labelling | GENENTECH, INC. (US) | 2013-05-07 | — | — | US | disclosed |
| US-20100221176-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | GENENTECH, INC. | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100221176-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | RAB5IF, RPS27A, PSMA6 | MMP2 2715/4885MMP9 4364/4885MMP8 2553/4885 |
| US-20130216475-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | RAB5IF, RPS27A, PSMA6 | MMP2 2715/4885MMP9 4364/4885MMP8 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.