Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | NCF1 | P14598 | 3/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450930 | 0.99 | DGAT1 (0.39) | GBA1DGAT1DRD2MMP2MMP9 | |
| SCHEMBL17776309 | 0.89 | CSNK2A1 (0.41) | DGAT1DRD2MMP2MMP9MMP8 | |
| SCHEMBL17776308 | 0.87 | DGAT1 (0.48) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL18768818 | 0.85 | EPHX2 (0.46) | DRD2HDAC1EPHX2 | |
| SCHEMBL16234065 | 0.85 | CSNK2A1 (0.40) | GBA1CSNK2A1HDAC1EPHX2 | |
| SCHEMBL24894084 | 0.84 | EPHX2 (0.51) | GBA1DRD2EPHX2 | |
| SCHEMBL24916753 | 0.83 | EPHX2 (0.53) | GBA1DRD2EPHX2 | |
| SCHEMBL23194394 | 0.83 | DRD2 (0.39) | DGAT1DRD2MMP2MMP9MMP8 | |
| SCHEMBL19652456 | 0.83 | DRD2 (0.39) | GBA1DGAT1DRD2CSNK2A1HDAC1 | |
| SCHEMBL16180807 | 0.83 | MMP2 (0.47) | DGAT1DRD2MMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207413-A1 | PROTEOLYSIS-TARGETING CHIMERIC MOLECULES (PROTACS) THAT INDUCE DEGRADATION OF C-MYC PROTEIN | NORTHWESTERN UNIVERSITY | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207413-A1 | PROTEOLYSIS-TARGETING CHIMERIC MOLECULES (PROTACS) THAT INDUCE DEGRADATION OF C-MYC PROTEIN | MYCBP, MYC, MYCBP2 | GBA1 4613/4885DGAT1 4314/4885DRD2 3492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.