Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12927419 | 0.87 | SMN1; SMN2 (0.40) | CASP1PTGS2NPC1RAB9APOLB | |
| SCHEMBL10066691 | 0.85 | PTGS2 (0.39) | CASP1PTGS2POLBSMN1; SMN2HTT | |
| SCHEMBL2754676 | 0.79 | HTT (0.39) | PTGS2SMN1; SMN2HTTMCL1PTGDR2 | |
| SCHEMBL14364642 | 0.79 | PTGS2 (0.40) | PTGS2SMN1; SMN2HTTMCL1PTGDR2 | |
| SCHEMBL13064140 | 0.79 | NPC1 (0.47) | CASP1PTGS2NPC1RAB9APOLB | |
| SCHEMBL10228504 | 0.78 | CNR2 (0.36) | PTGS2CYP2C9MAPTSMN1; SMN2HTT | |
| SCHEMBL12906864 | 0.77 | DHODH (0.37) | MAPTPTGDR2DHODHPPARGPPARD | |
| SCHEMBL13668496 | 0.77 | SMN1; SMN2 (0.46) | PTGS2NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL857384 | 0.76 | NPC1 (0.43) | NPC1RAB9APOLBCYP2C9MAPT | |
| SCHEMBL13266193 | 0.76 | HTT (0.43) | CASP1PTGS2CYP2C9SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1862489-B1 | Block Copolymer and Use Thereof | SUMITOMO CHEMICAL CO (JP) | 2010-10-06 | — | — | EP | disclosed |