SCHEMBL9844594

SCHEMBL9844594

CCCc1cccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(C)cc3)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 2/20 0.41
CTSS P25774 1/20 0.40
CTSK P43235 1/20 0.40
HTR7 P34969 3/20 0.40
BCL2 P10415 1/20 0.40
AOC3 Q16853 2/20 0.39
CYP2C19 P33261 1/20 0.39
CNR2 P34972 1/20 0.38
BACE1 P56817 1/20 0.37
MPO P05164 1/20 0.37
PTPN5 P54829 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9321881 0.88 FFAR1 (0.45) FFAR1HTR7BCL2AOC3CYP2C19
SCHEMBL24478732 0.85 CYP2C19 (0.42) CYP2C19CNR2
SCHEMBL21392007 0.85 CYP2C19 (0.42) CYP2C19CNR2
SCHEMBL15681410 0.83 LPL (0.44) CYP2C19CNR2
SCHEMBL24525857 0.82 DHODH (0.44) PTPN5
SCHEMBL24005570 0.82 CTSS (0.50) CTSSCTSKHTR7BCL2CNR2
SCHEMBL12533859 0.82 LTB4R2 (0.40) CTSSCTSKBCL2CYP2C19CNR2
SCHEMBL12374378 0.81 LPL (0.42) CYP2C19CNR2
SCHEMBL18286383 0.81 LTB4R2 (0.41) FFAR1CNR2
SCHEMBL8071178 0.81 HTR7 (0.46) CTSSCTSKHTR7CYP2C19CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409160-A2 Electrophotographic recording elements containing a combination of photoconductive perylene materials EASTMAN KODAK COMPANY (US) 1991-01-23 EP disclosed
US-4968571-A PHOTOSENSITIVITY, DURABILITY EASTMAN KODAK COMPANY (US) 1990-11-06 US disclosed