Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | RHOC | P08134 | 1/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.53 |
| ▸ | PHGDH | O43175 | 2/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13148217 | 0.89 | ALDH1A1 (0.66) | ALDH1A1KMT2APHGDHPKMPRKAB2 | |
| SCHEMBL13148215 | 0.82 | ALDH1A1 (0.61) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL13148180 | 0.81 | KMT2A (0.68) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL13148206 | 0.81 | ALDH1A1 (0.62) | ALDH1A1LMNAPOLBKDM4EKMT2A | |
| SCHEMBL19357207 | 0.79 | GAA (0.64) | ALDH1A1LMNAKDM4EKMT2AMEN1 | |
| SCHEMBL17266617 | 0.77 | KMT2A (0.74) | ALDH1A1LMNAPOLBKMT2AMEN1 | |
| SCHEMBL3080673 | 0.76 | ALDH1A1 (0.74) | ALDH1A1LMNAPOLBKDM4EKMT2A | |
| SCHEMBL3086858 | 0.73 | ALDH1A1 (0.77) | ALDH1A1LMNAPOLBKDM4EKMT2A | |
| SCHEMBL4270479 | 0.73 | L3MBTL1 (0.80) | ALDH1A1LMNAL3MBTL1USP2 | |
| SCHEMBL23447713 | 0.73 | P2RX1 (1.00) | P2RX1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234377-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2010-09-16 | — | — | US | disclosed |
| US-20100234377-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2010-09-16 | — | — | US | disclosed |
| WO-2008122787-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234377-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | HPGDS, PTGDR, PTGIS | ALDH1A1 614/4885P2RX1 50/4885LMNA 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.