Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 7/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180670 | 0.84 | IDO1 (0.41) | IDO1APP | |
| SCHEMBL12772124 | 0.81 | IDO1 (0.46) | IDO1AGXTAPPSLC6A4ALDH1A1 | |
| SCHEMBL21996211 | 0.81 | IDO1 (0.46) | IDO1AGXTAPPSLC6A4ALDH1A1 | |
| SCHEMBL31388986 | 0.81 | ALDH1A1 (0.53) | IDO1AGXTAPPSLC6A4ALDH1A1 | |
| SCHEMBL13149244 | 0.81 | ALDH1A1 (0.53) | IDO1AGXTAPPSLC6A4ALDH1A1 | |
| SCHEMBL12770001 | 0.80 | IDO1 (0.42) | IDO1AGXTAPPSLC6A4ALDH1A1 | |
| SCHEMBL28885907 | 0.76 | IDO1 (0.52) | IDO1AGXTAPPSLC6A4MAOB | |
| SCHEMBL13149137 | 0.76 | IDO1 (0.39) | IDO1AGXTAPPSLC6A4ALDH1A1 | |
| SCHEMBL12714251 | 0.75 | IDO1 (0.50) | IDO1AGXTAPPSLC6A4TSHR | |
| SCHEMBL13410636 | 0.75 | IDO1 (0.50) | IDO1AGXTAPPSLC6A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513440-B2 | Compositions and methods comprising analogues of radicicol A | UNIVERSITE DE STRASBOURG (FR) | 2013-08-20 | — | — | US | disclosed |
| US-20100233279-A1 | Compositions And Methods Comprising Analogues Of Radicicol A | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233279-A1 | Compositions And Methods Comprising Analogues Of Radicicol A | CSNK1A1L, CSNK1A1, ALPL | IDO1 4396/4885AGXT 3174/4885APP 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.