Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 5/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13180671 | 0.87 | IDO1 (0.33) | IDO1 | |
| SCHEMBL13180585 | 0.85 | HRH3 (0.34) | — | |
| SCHEMBL13149138 | 0.76 | IDO1 (0.47) | IDO1AGXTSLC6A4APPCA1 | |
| SCHEMBL22894852 | 0.75 | PYCR1 (0.32) | SLC6A4UCHL1GLANPSR1 | |
| SCHEMBL25209623 | 0.73 | APLNR (0.45) | — | |
| SCHEMBL22894851 | 0.73 | APLNR (0.45) | — | |
| SCHEMBL28686206 | 0.72 | CA1 (0.37) | CA1CA2ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL21996211 | 0.72 | IDO1 (0.46) | IDO1AGXTSLC6A4APPALDH1A1 | |
| SCHEMBL13149244 | 0.72 | ALDH1A1 (0.53) | IDO1AGXTSLC6A4APPCA1 | |
| SCHEMBL12772124 | 0.72 | IDO1 (0.46) | IDO1AGXTSLC6A4APPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8513440-B2 | Compositions and methods comprising analogues of radicicol A | UNIVERSITE DE STRASBOURG (FR) | 2013-08-20 | — | — | US | disclosed |
| US-20100233279-A1 | Compositions And Methods Comprising Analogues Of Radicicol A | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233279-A1 | Compositions And Methods Comprising Analogues Of Radicicol A | CSNK1A1L, CSNK1A1, ALPL | IDO1 4396/4885AGXT 3174/4885SLC6A4 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.