Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149368 | 0.87 | LMNA (0.56) | KDM4EALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL13149845 | 0.80 | ALDH1A1 (0.52) | SIGMAR1ALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL13149852 | 0.79 | MEN1 (0.50) | SIGMAR1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13149714 | 0.77 | EPHX2 (0.51) | KDM4EALDH1A1MEN1KMT2AALOX15 | |
| SCHEMBL15961276 | 0.77 | SIGMAR1 (0.91) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13149947 | 0.77 | TSHR (0.61) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL17695832 | 0.77 | SIGMAR1 (0.76) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13149936 | 0.76 | ALDH1A1 (0.55) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL27564901 | 0.75 | SIGMAR1 (0.73) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL13242427 | 0.74 | NR2E1 (0.53) | ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2013-03-21 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338430-B2 | N-substituted piperazines | DOW AGROSCIENCES, LLC. (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | DOW AGROSCIENCES LLC (US) | 2010-09-16 | — | — | US | disclosed |
| US-7754724-B2 | N-substituted piperazines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754724-B2 | N-substituted piperazines | DOW AGROSCIENCES LLC (US) | 2010-07-13 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
| US-20070004750-A1 | N-substituted piperazines | CORTEVA AGRISCIENCE LLC | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004750-A1 | N-substituted piperazines | PRXL2A, CNPY2, CYP4X1 | SIGMAR1 251/4885KDM4E 280/4885ALDH1A1 641/4885 |
| US-20100234391-A1 | N-SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | SIGMAR1 251/4885KDM4E 280/4885ALDH1A1 641/4885 |
| US-20130072497-A1 | N- SUBSTITUTED PIPERAZINES | PRXL2A, CNPY2, CYP4X1 | SIGMAR1 251/4885KDM4E 280/4885ALDH1A1 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.