Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.43 |
| ▸ | ESR1 | P03372 | 9/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SHBG | P04278 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13149650 | 0.89 | LMNA (0.52) | LMNATYRTSHRESR2ESR1 | |
| SCHEMBL469946 | 0.89 | TSHR (0.55) | ACHETSHRALDH1A1APPGAA | |
| SCHEMBL11670031 | 0.89 | ACHE (0.68) | ACHELMNATYRTSHRESR2 | |
| SCHEMBL10326579 | 0.89 | ACHE (0.68) | ACHELMNATYRTSHRESR2 | |
| SCHEMBL12574819 | 0.89 | ACHE (0.68) | ACHELMNATYRTSHRESR2 | |
| SCHEMBL3097103 | 0.89 | LMNA (0.52) | LMNATYRTSHRESR2ESR1 | |
| SCHEMBL470004 | 0.83 | TSHR (0.48) | ACHETSHRHPGDHSD17B10ALDH1A1 | |
| SCHEMBL4754769 | 0.83 | TSHR (0.48) | ACHETSHRHPGDHSD17B10ALDH1A1 | |
| SCHEMBL23661307 | 0.81 | TSHR (0.46) | ACHELMNATSHRESR2ESR1 | |
| SCHEMBL11481828 | 0.81 | ESR1 (0.59) | ACHELMNATYRTSHRESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799949-B2 | Tetraphenylmethane skeleton-containing compound | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227812-A1 | TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND | PAH, TSNAX, ZFX | ACHE 3666/4885LMNA 2152/4885TYR 106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.