Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29589463 | 1.00 | DRD1 (0.58) | DRD1 | |
| SCHEMBL29883736 | 1.00 | DRD1 (0.58) | DRD1 | |
| SCHEMBL15883111 | 0.92 | DRD1 (0.51) | DRD1 | |
| SCHEMBL10048474 | 0.85 | DRD1 (0.45) | DRD1 | |
| SCHEMBL709261 | 0.79 | DRD1 (0.64) | DRD1 | |
| SCHEMBL29867522 | 0.79 | DRD1 (0.64) | DRD1 | |
| SCHEMBL16987374 | 0.79 | DRD1 (0.51) | DRD1 | |
| SCHEMBL15871415 | 0.78 | DRD1 (0.62) | DRD1 | |
| SCHEMBL21374252 | 0.78 | DRD1 (0.62) | DRD1 | |
| SCHEMBL30066813 | 0.78 | DRD1 (0.62) | DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 315 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388564-A1 | METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS | EDGEWISE THERAPEUTICS INC (US) | 2025-12-25 | — | — | US | claimed |
| EP-4522599-A1 | METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS | EDGEWISE THERAPEUTICS, INC. (US) | 2025-03-19 | — | — | EP | claimed |
| EP-3694864-B1 | BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF | QPEX BIOPHARMA INC (US) | 2025-03-05 | — | — | EP | claimed |
| CN-119317621-A | Process for preparing pyridazinone compounds | 艾知怀斯治疗学公司 | 2025-01-14 | — | — | CN | claimed |
| US-20240279399-A1 | POLYMERS FOR USE IN ELECTRONIC DEVICES | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2024-08-22 | — | — | US | claimed |
| WO-2023220180-A1 | METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS | EDGEWISE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | claimed |
| CN-116368134-A | Methods of making ubiquitin JAK inhibitors and related intermediate compounds | 施万生物制药研发IP有限责任公司 | 2023-06-30 | — | — | CN | claimed |
| CN-115612310-A | Porphyrin photosensitive dye and application thereof | 杭州中美华东制药有限公司 | 2023-01-17 | — | — | CN | claimed |
| US-11286270-B2 | Boronic acid derivatives and synthesis thereof | QPEX BIOPHARMA, INC. (US) | 2022-03-29 | — | — | US | claimed |
| US-20200407373-A1 | BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF | QPEX BIOPHARMA, INC. | 2020-12-31 | — | — | US | claimed |
| WO-2019075084-A1 | BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF | QPEX BIOPHARMA, INC. (US) | 2019-04-18 | — | — | WO | claimed |
| US-10053426-B2 | Process for the synthesis of metyrapone and alkylated metyrapone analogs | ALBEMARLE CORPORATION (US) | 2018-08-21 | — | — | US | claimed |
| EP-3237383-A1 | ONE-STEP PROCESS FOR THE SYNTHESIS OF ALKYLATED METYRAPONE ANALOGS | Albemarle Corporation (US) | 2017-11-01 | — | — | EP | claimed |
| WO-2016105619-A1 | ONE-STEP PROCESS FOR THE SYNTHESIS OF ALKYLATED METYRAPONE ANALOGS | ALBEMARLE CORPORATION (US) | 2016-06-30 | — | — | WO | claimed |
| CN-105601495-A | Synthesis method of netupitant intermediates | HEFEI LEAF BIO-TECH CO LTD | 2016-05-25 | — | — | CN | claimed |
| CN-105541594-A | Synthetic method for netupitant intermediate 2-(3,5-bistrifluoromethylphenyl)-2-methyl propionate | HEFEI LIFU BIOTECHNOLOGY CO LTD | 2016-05-04 | — | — | CN | claimed |
| CN-105541593-A | Method for synthesizing drug intermediate | HEFEI LIFU BIOTECHNOLOGY CO LTD | 2016-05-04 | — | — | CN | claimed |
| CN-105523916-A | Method for synthetizing Netupitant midbody impurity 2-(3,5-Bis-trifluoromethyl-phenyl) propionic acid | INST OF ADVANCED TECH UNIV OF SCIENCE AND TECH OF CHINA | 2016-04-27 | — | — | CN | claimed |
| CN-104447679-B | The preparation method of a kind of 2 thiophene acetonitrile and 2 thiophene ethyl amine | Advanced technology research institute of China Science & Technology University (CN) | 2016-04-13 | — | — | CN | claimed |
| CN-104447679-A | 2-thiopheneacetonitrile and 2-thiopheneethylamine preparing method | INST ADVANCED TECHNOLOGY UNIV SCIENCE & TECHNOLOGY CHINA | 2015-03-25 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388564-A1 | METHODS OF MANUFACTURING PYRIDAZINONE COMPOUNDS | MUSK, SMN1; SMN2, PAX3 | DRD1 887/4885 |
| US-20200407373-A1 | BORONIC ACID DERIVATIVES AND SYNTHESIS THEREOF | BTD, BLVRB, BLK | DRD1 3180/4885 |
| US-10053426-B2 | Process for the synthesis of metyrapone and alkylated metyrapone analogs | MET, ABL1, CMPK1 | DRD1 38/4885 |
| US-11286270-B2 | Boronic acid derivatives and synthesis thereof | BTD, BLVRB, BLK | DRD1 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.