Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13151696 | 0.90 | MAPT (0.44) | MAPTALDH1A1MTNR1BKDM4EHPGD | |
| SCHEMBL13153378 | 0.90 | NPC1 (0.42) | MAPTALDH1A1MTNR1BKDM4EHPGD | |
| SCHEMBL10097656 | 0.89 | PFKFB2 (0.48) | MAPTALDH1A1MTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL13152055 | 0.89 | MTNR1A (0.46) | MAPTALDH1A1MTNR1BKDM4EHPGD | |
| SCHEMBL10095367 | 0.87 | MAPT (0.43) | MAPTALDH1A1MTNR1BKDM4EHPGD | |
| SCHEMBL10097607 | 0.87 | MTNR1A (0.46) | MAPTALDH1A1MTNR1BKDM4EHPGD | |
| SCHEMBL10249955 | 0.85 | MTNR1A (0.46) | MAPTALDH1A1MTNR1BKDM4EHPGD | |
| SCHEMBL10097294 | 0.84 | MAPT (0.41) | MAPTALDH1A1MTNR1BSMN1; SMN2LMNA | |
| SCHEMBL10249312 | 0.84 | MTNR1A (0.42) | MAPTMTNR1BKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL13152174 | 0.84 | L3MBTL1 (0.42) | MAPTALDH1A1MTNR1BKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |