Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10097782 | 0.91 | L3MBTL1 (0.42) | L3MBTL1MAPTALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13152055 | 0.89 | MTNR1A (0.46) | MAPTALDH1A1MTNR1AMTNR1BNPC1 | |
| SCHEMBL10097656 | 0.89 | PFKFB2 (0.48) | MAPTALDH1A1MTNR1AMTNR1BRORC | |
| SCHEMBL13153378 | 0.88 | NPC1 (0.42) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10097607 | 0.87 | MTNR1A (0.46) | L3MBTL1MAPTALDH1A1MTNR1AMTNR1B | |
| SCHEMBL13152172 | 0.84 | MAPT (0.44) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10249955 | 0.82 | MTNR1A (0.46) | MAPTALDH1A1TSHRMTNR1AMTNR1B | |
| SCHEMBL10256083 | 0.82 | KMT2A (0.50) | MAPTALDH1A1MTNR1AMTNR1BRORC | |
| SCHEMBL10249312 | 0.81 | MTNR1A (0.42) | MAPTMTNR1AMTNR1BNPC1RAB9A | |
| SCHEMBL10097294 | 0.81 | MAPT (0.41) | MAPTALDH1A1MTNR1BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |