Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984051 | 0.69 | MKNK2 (0.41) | KDM4EALDH1A1TSHRGAAHSD17B10 | |
| SCHEMBL10095290 | 0.69 | RAB9A (0.46) | KDM4EALDH1A1TSHRHSD17B10NPC1 | |
| SCHEMBL982072 | 0.68 | MKNK2 (0.42) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL980446 | 0.68 | NPC1 (0.50) | PTPN1ALDH1A1HSD17B10NPC1MAPT | |
| SCHEMBL10095258 | 0.68 | GABRA1 (0.45) | KDM4EALDH1A1TSHRGAAHSD17B10 | |
| SCHEMBL982376 | 0.68 | ALDH1A1 (0.40) | KDM4EALDH1A1TSHRHSD17B10NPC1 | |
| SCHEMBL2433501 | 0.67 | ALDH1A1 (0.50) | KDM4EALDH1A1TSHRGAAHSD17B10 | |
| SCHEMBL982663 | 0.67 | NOTUM (0.52) | KDM4EALDH1A1TSHRHSD17B10L3MBTL1 | |
| SCHEMBL980895 | 0.67 | MAPT (0.48) | KDM4EALDH1A1TSHRGAAHSD17B10 | |
| SCHEMBL7850213 | 0.67 | HTR6 (0.49) | KDM4EALDH1A1TSHRGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |