Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 8/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13153267 | 0.86 | PTGER4 (0.42) | CYP3A4TSHRALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL18015855 | 0.79 | KCNH2 (0.46) | KCNA3HTR6MAT2ACNR1PTGER4 | |
| SCHEMBL13152683 | 0.79 | LMNA (0.41) | HTR6CNR1 | |
| SCHEMBL13153386 | 0.77 | KIF11 (0.44) | KCNA3HTR6ALDH1A1MAT2ACNR1 | |
| SCHEMBL13806217 | 0.77 | CYP3A4 (0.41) | HTR6CYP3A4NR4A2TSHRALDH1A1 | |
| SCHEMBL2884083 | 0.76 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL2642676 | 0.74 | KDM4E (0.48) | NR4A2TSHRALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL18014779 | 0.74 | PTGER1 (0.46) | KCNA3HTR6SCN2ACNR1PTGER4 | |
| SCHEMBL13806314 | 0.74 | NR4A2 (0.50) | NR4A2ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL13152546 | 0.73 | CYP1A2 (0.41) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118009-A1 | HCV INHIBITOR AND THERAPEUTIC AGENT COMBINATIONS | PTC THERAPEUTICS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |