Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 4/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 8/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13153747 | 0.82 | LMNA (0.56) | S1PR3SLC6A9SLC6A5HPGDSS1PR1 | |
| SCHEMBL28466269 | 0.79 | HPGDS (0.72) | S1PR3S1PR4SLC6A9SLC6A5CNR1 | |
| SCHEMBL27282532 | 0.79 | CNR1 (0.53) | SLC6A9SLC6A5CNR1CACNA2D1CACNA1B | |
| SCHEMBL11551169 | 0.75 | CNR1 (0.53) | SLC6A9SLC6A5CNR1CACNA2D1CACNA1B | |
| SCHEMBL9023826 | 0.75 | HPGDS (0.41) | S1PR3SLC6A9SLC6A5GAAHPGDS | |
| SCHEMBL17663900 | 0.75 | S1PR3 (0.60) | S1PR3S1PR4SLC6A9SLC6A5KDM4E | |
| SCHEMBL30530178 | 0.74 | SLC6A9 (0.71) | S1PR3S1PR4SLC6A9SLC6A5CNR1 | |
| SCHEMBL304995 | 0.73 | CNR1 (0.48) | S1PR3S1PR4SLC6A9SLC6A5CNR1 | |
| Iodide SCHEMBL11335601 | 0.73 | CNR1 (0.51) | SLC6A9SLC6A5CNR1CACNA2D1CACNA1B | |
| SCHEMBL27396355 | 0.73 | ALDH1A1 (0.50) | S1PR3S1PR4KDM4EGAAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010123150-A1 | 2-ARYL IMIDAZOLINE DERIVATIVES | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-10-28 | — | — | WO | disclosed |